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Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug.
Wu H, Esteve E, Tremaroli V, Khan MT, Caesar R, Mannerås-Holm L, Ståhlman M, Olsson LM, Serino M, Planas-Fèlix M, Xifra G, Mercader JM, Torrents D, Burcelin R, Ricart W, Perkins R, Fernàndez-Real JM, Bäckhed F. Wu H, et al. Among authors: khan mt. Nat Med. 2017 Jul;23(7):850-858. doi: 10.1038/nm.4345. Epub 2017 May 22. Nat Med. 2017. PMID: 28530702 Clinical Trial.
Microbial modulation of insulin sensitivity.
Khan MT, Nieuwdorp M, Bäckhed F. Khan MT, et al. Cell Metab. 2014 Nov 4;20(5):753-760. doi: 10.1016/j.cmet.2014.07.006. Cell Metab. 2014. PMID: 25176147 Free article.
Dynamics and Stabilization of the Human Gut Microbiome during the First Year of Life.
Bäckhed F, Roswall J, Peng Y, Feng Q, Jia H, Kovatcheva-Datchary P, Li Y, Xia Y, Xie H, Zhong H, Khan MT, Zhang J, Li J, Xiao L, Al-Aama J, Zhang D, Lee YS, Kotowska D, Colding C, Tremaroli V, Yin Y, Bergman S, Xu X, Madsen L, Kristiansen K, Dahlgren J, Wang J. Bäckhed F, et al. Among authors: khan mt. Cell Host Microbe. 2015 May 13;17(5):690-703. doi: 10.1016/j.chom.2015.04.004. Cell Host Microbe. 2015. PMID: 25974306 Free article.
Microbially Produced Imidazole Propionate Impairs Insulin Signaling through mTORC1.
Koh A, Molinaro A, Ståhlman M, Khan MT, Schmidt C, Mannerås-Holm L, Wu H, Carreras A, Jeong H, Olofsson LE, Bergh PO, Gerdes V, Hartstra A, de Brauw M, Perkins R, Nieuwdorp M, Bergström G, Bäckhed F. Koh A, et al. Among authors: khan mt. Cell. 2018 Nov 1;175(4):947-961.e17. doi: 10.1016/j.cell.2018.09.055. Epub 2018 Oct 25. Cell. 2018. PMID: 30401435 Free article.
Donor metabolic characteristics drive effects of faecal microbiota transplantation on recipient insulin sensitivity, energy expenditure and intestinal transit time.
de Groot P, Scheithauer T, Bakker GJ, Prodan A, Levin E, Khan MT, Herrema H, Ackermans M, Serlie MJM, de Brauw M, Levels JHM, Sales A, Gerdes VE, Ståhlman M, Schimmel AWM, Dallinga-Thie G, Bergman JJ, Holleman F, Hoekstra JBL, Groen A, Bäckhed F, Nieuwdorp M. de Groot P, et al. Among authors: khan mt. Gut. 2020 Mar;69(3):502-512. doi: 10.1136/gutjnl-2019-318320. Epub 2019 May 30. Gut. 2020. PMID: 31147381 Free PMC article.
Dynamics of the normal gut microbiota: A longitudinal one-year population study in Sweden.
Olsson LM, Boulund F, Nilsson S, Khan MT, Gummesson A, Fagerberg L, Engstrand L, Perkins R, Uhlén M, Bergström G, Tremaroli V, Bäckhed F. Olsson LM, et al. Among authors: khan mt. Cell Host Microbe. 2022 May 11;30(5):726-739.e3. doi: 10.1016/j.chom.2022.03.002. Epub 2022 Mar 28. Cell Host Microbe. 2022. PMID: 35349787 Free article.
514 results