Khan I - Search Results

1

Designing Next-Generation Drug-like Molecules for Medicinal Applications.

Khan I, Zaib S. Khan I, et al. Molecules. 2023 Feb 16;28(4):1860. doi: 10.3390/molecules28041860. Molecules. 2023. PMID: 36838848 Free PMC article.

2

Synthesis, crystal structure and biological evaluation of some novel 1,2,4-triazolo[3,4-b]-1,3,4-thiadiazoles and 1,2,4-triazolo[3,4-b]-1,3,4-thiadiazines.

Khan I, Zaib S, Ibrar A, Rama NH, Simpson J, Iqbal J. Khan I, et al. Eur J Med Chem. 2014 May 6;78:167-77. doi: 10.1016/j.ejmech.2014.03.046. Epub 2014 Mar 19. Eur J Med Chem. 2014. PMID: 24681981

3

Active compounds from a diverse library of triazolothiadiazole and triazolothiadiazine scaffolds: synthesis, crystal structure determination, cytotoxicity, cholinesterase inhibitory activity, and binding mode analysis.

Khan I, Ibrar A, Zaib S, Ahmad S, Furtmann N, Hameed S, Simpson J, Bajorath J, Iqbal J. Khan I, et al. Bioorg Med Chem. 2014 Nov 1;22(21):6163-73. doi: 10.1016/j.bmc.2014.08.026. Epub 2014 Sep 6. Bioorg Med Chem. 2014. PMID: 25257911

4

Quinazolines and quinazolinones as ubiquitous structural fragments in medicinal chemistry: An update on the development of synthetic methods and pharmacological diversification.

Khan I, Zaib S, Batool S, Abbas N, Ashraf Z, Iqbal J, Saeed A. Khan I, et al. Bioorg Med Chem. 2016 Jun 1;24(11):2361-2381. doi: 10.1016/j.bmc.2016.03.031. Epub 2016 Mar 18. Bioorg Med Chem. 2016. PMID: 27112448 Review.

5

Symmetrical aryl linked bis-iminothiazolidinones as new chemical entities for the inhibition of monoamine oxidases: Synthesis, in vitro biological evaluation and molecular modelling analysis.

Abbas N, Zaib S, Bakht SM, Ibrar A, Khan I, Batool S, Saeed A, Iqbal J. Abbas N, et al. Among authors: khan i. Bioorg Chem. 2017 Feb;70:17-26. doi: 10.1016/j.bioorg.2016.11.004. Epub 2016 Nov 9. Bioorg Chem. 2017. PMID: 27863747

6

Quinolinic Carboxylic Acid Derivatives as Potential Multi-target Compounds for Neurodegeneration: Monoamine Oxidase and Cholinesterase Inhibition.

Khan NA, Khan I, Abid SMA, Zaib S, Ibrar A, Andleeb H, Hameed S, Iqbal J. Khan NA, et al. Among authors: khan i. Med Chem. 2018;14(1):74-85. doi: 10.2174/1573406413666170525125231. Med Chem. 2018. PMID: 28545383

7

Exploration of aroyl/heteroaroyl iminothiazolines featuring 2,4,5-trichlorophenyl moiety as a new class of potent, selective, and in vitro efficacious glucosidase inhibitors.

Kazmi M, Zaib S, Amjad ST, Khan I, Ibrar A, Saeed A, Iqbal J. Kazmi M, et al. Among authors: khan i. Bioorg Chem. 2017 Oct;74:134-144. doi: 10.1016/j.bioorg.2017.07.012. Epub 2017 Jul 25. Bioorg Chem. 2017. PMID: 28780150

8

A new entry into the portfolio of α-glucosidase inhibitors as potent therapeutics for type 2 diabetes: Design, bioevaluation and one-pot multi-component synthesis of diamine-bridged coumarinyl oxadiazole conjugates.

Kazmi M, Zaib S, Ibrar A, Amjad ST, Shafique Z, Mehsud S, Saeed A, Iqbal J, Khan I. Kazmi M, et al. Among authors: khan i. Bioorg Chem. 2018 Apr;77:190-202. doi: 10.1016/j.bioorg.2017.12.022. Epub 2018 Jan 16. Bioorg Chem. 2018. PMID: 29421697

9

Probing the high potency of pyrazolyl pyrimidinetriones and thioxopyrimidinediones as selective and efficient non-nucleotide inhibitors of recombinant human ectonucleotidases.

Andleeb H, Hameed S, Ejaz SA, Khan I, Zaib S, Lecka J, Sévigny J, Iqbal J. Andleeb H, et al. Among authors: khan i. Bioorg Chem. 2019 Jul;88:102893. doi: 10.1016/j.bioorg.2019.03.067. Epub 2019 Apr 2. Bioorg Chem. 2019. PMID: 30986550

10

New Hybrid Scaffolds Based on Carbazole-Chalcones as Potent Anticancer Agents.

Rashid F, Zaib S, Ibrar A, Ejaz SA, Saeed A, Iqbal J, Khan I. Rashid F, et al. Among authors: khan i. Anticancer Agents Med Chem. 2021;21(9):1082-1091. doi: 10.2174/1871520620666200721110732. Anticancer Agents Med Chem. 2021. PMID: 32698741

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