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TLR4 is one of the receptors for Chikungunya virus envelope protein E2 and regulates virus induced pro-inflammatory responses in host macrophages.
Mahish C, De S, Chatterjee S, Ghosh S, Keshry SS, Mukherjee T, Khamaru S, Tung KS, Subudhi BB, Chattopadhyay S, Chattopadhyay S. Mahish C, et al. Among authors: khamaru s. Front Immunol. 2023 Apr 20;14:1139808. doi: 10.3389/fimmu.2023.1139808. eCollection 2023. Front Immunol. 2023. PMID: 37153546 Free PMC article.
Telmisartan Restricts Chikungunya Virus Infection In Vitro and In Vivo through the AT1/PPAR-γ/MAPKs Pathways.
De S, Mamidi P, Ghosh S, Keshry SS, Mahish C, Pani SS, Laha E, Ray A, Datey A, Chatterjee S, Singh S, Mukherjee T, Khamaru S, Chattopadhyay S, Subudhi BB, Chattopadhyay S. De S, et al. Among authors: khamaru s. Antimicrob Agents Chemother. 2022 Jan 18;66(1):e0148921. doi: 10.1128/AAC.01489-21. Epub 2021 Nov 8. Antimicrob Agents Chemother. 2022. PMID: 34748384 Free PMC article.