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Evaluation of novel 2-(quinoline-2-ylthio)acetamide derivatives linked to diphenyl-imidazole as α-glucosidase inhibitors: Insights from in silico, in vitro, and in vivo studies on their anti-diabetic properties.
Khalili Ghomi M, Noori M, Mirahmad M, Iraji A, Sadr AS, Dastyafteh N, Asili P, Gholami M, Javanshir S, Lotfi M, Mojtabavi S, Faramarzi MA, Asadi M, Nasli-Esfahani E, Palimi M, Larijani B, Meshkatalsadat MH, Mahdavi M. Khalili Ghomi M, et al. Eur J Med Chem. 2024 Apr 5;269:116332. doi: 10.1016/j.ejmech.2024.116332. Epub 2024 Mar 16. Eur J Med Chem. 2024. PMID: 38508120
Alpha-glucosidase inhibitory and hypoglycemic effects of imidazole-bearing thioquinoline derivatives with different substituents: In silico, in vitro, and in vivo evaluations.
Azmi A, Noori M, Khalili Ghomi M, Nazari Montazer M, Iraji A, Dastyafteh N, Oliyaei N, Khoramjouy M, Rezaei Z, Javanshir S, Mojtabavi S, Faramarzi MA, Asadi M, Faizi M, Mahdavi M. Azmi A, et al. Among authors: khalili ghomi m. Bioorg Chem. 2024 Mar;144:107106. doi: 10.1016/j.bioorg.2024.107106. Epub 2024 Jan 8. Bioorg Chem. 2024. PMID: 38244380
Aryl-quinoline-4-carbonyl hydrazone bearing different 2-methoxyphenoxyacetamides as potent α-glucosidase inhibitors; molecular dynamics, kinetic and structure-activity relationship studies.
Hamedifar H, Mirfattahi M, Khalili Ghomi M, Azizian H, Iraji A, Noori M, Moazzam A, Dastyafteh N, Nokhbehzaim A, Mehrpour K, Javanshir S, Mojtabavi S, Faramarzi MA, Larijani B, Hajimiri MH, Mahdavi M. Hamedifar H, et al. Among authors: khalili ghomi m. Sci Rep. 2024 Jan 3;14(1):388. doi: 10.1038/s41598-023-50395-8. Sci Rep. 2024. PMID: 38172167 Free PMC article.
Phenyl-quinoline derivatives as lead structure of cholinesterase inhibitors with potency to reduce the GSK-3β level targeting Alzheimer's disease.
Noori M, Dastyafteh N, Safapoor S, Khalili Ghomi M, Tanideh R, Zomorodian K, Hamedifar H, Dara M, Zare S, Irajie C, Javanshir S, Rastegar H, Panahi N, Larijani B, Mahdavi M, Hajimiri MH, Iraji A. Noori M, et al. Among authors: khalili ghomi m. Int J Biol Macromol. 2023 Dec 31;253(Pt 7):127392. doi: 10.1016/j.ijbiomac.2023.127392. Epub 2023 Oct 11. Int J Biol Macromol. 2023. PMID: 37827412
[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives as new therapeutic candidates against urease positive microorganisms: design, synthesis, pharmacological evaluations, and in silico studies.
Khalili Ghomi M, Noori M, Nazari Montazer M, Zomorodian K, Dastyafteh N, Yazdanpanah S, Sayahi MH, Javanshir S, Nouri A, Asadi M, Badali H, Larijani B, Irajie C, Iraji A, Mahdavi M. Khalili Ghomi M, et al. Sci Rep. 2023 Jun 22;13(1):10136. doi: 10.1038/s41598-023-37203-z. Sci Rep. 2023. PMID: 37349372 Free PMC article.
Synthesis and structure-activity relationship studies of benzimidazole-thioquinoline derivatives as α-glucosidase inhibitors.
Moghadam Farid S, Noori M, Nazari Montazer M, Khalili Ghomi M, Mollazadeh M, Dastyafteh N, Irajie C, Zomorodian K, Mirfazli SS, Mojtabavi S, Faramarzi MA, Larijani B, Iraji A, Mahdavi M. Moghadam Farid S, et al. Among authors: khalili ghomi m. Sci Rep. 2023 Mar 16;13(1):4392. doi: 10.1038/s41598-023-31080-2. Sci Rep. 2023. PMID: 36928433 Free PMC article.
Thioquinoline derivatives conjugated to thiosemicarbazide as potent tyrosinase inhibitors with anti-melanogenesis properties.
Noori M, Sabourian R, Tasharoie A, Safavi M, Iraji A, Khalili Ghomi M, Dastyafteh N, Irajie C, Zarenezhad E, Mostafavi Pour SM, Rasekh F, Larijani B, Amini M, Hajimahmoodi M, Mahdavi M. Noori M, et al. Among authors: khalili ghomi m. Sci Rep. 2023 Feb 13;13(1):2578. doi: 10.1038/s41598-023-28852-1. Sci Rep. 2023. PMID: 36782003 Free PMC article.
New thioxothiazolidinyl-acetamides derivatives as potent urease inhibitors: design, synthesis, in vitro inhibition, and molecular dynamic simulation.
Dastyafteh N, Noori M, Nazari Montazer M, Zomorodian K, Yazdanpanah S, Iraji A, Khalili Ghomi M, Javanshir S, Asadi M, Dianatpour M, Biglar M, Larijani B, Amanlou M, Mahdavi M. Dastyafteh N, et al. Among authors: khalili ghomi m. Sci Rep. 2023 Jan 2;13(1):21. doi: 10.1038/s41598-022-27234-3. Sci Rep. 2023. PMID: 36593349 Free PMC article.