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[No title available]
[No authors listed] [No authors listed] PMID: 35552611
Characterization of Dual-Acting A3 Adenosine Receptor Positive Allosteric Modulators That Preferentially Enhance Adenosine-Induced Gαi3 and GαoA Isoprotein Activation.
Fisher CL, Fallot LB, Wan TC, Keyes RF, Suresh RR, Rothwell AC, Gao ZG, McCorvy JD, Smith BC, Jacobson KA, Auchampach JA. Fisher CL, et al. Among authors: keyes rf. ACS Pharmacol Transl Sci. 2022 Jul 15;5(8):625-641. doi: 10.1021/acsptsci.2c00076. eCollection 2022 Aug 12. ACS Pharmacol Transl Sci. 2022. PMID: 35983277 Free PMC article.
N-{3-[2-(4-alkoxyphenoxy)thiazol-5-yl]-1-methylprop-2-ynyl}carboxy derivatives as acetyl-coA carboxylase inhibitors--improvement of cardiovascular and neurological liabilities via structural modifications.
Gu YG, Weitzberg M, Clark RF, Xu X, Li Q, Lubbers NL, Yang Y, Beno DW, Widomski DL, Zhang T, Hansen TM, Keyes RF, Waring JF, Carroll SL, Wang X, Wang R, Healan-Greenberg CH, Blomme EA, Beutel BA, Sham HL, Camp HS. Gu YG, et al. Among authors: keyes rf. J Med Chem. 2007 Mar 8;50(5):1078-82. doi: 10.1021/jm070035a. Epub 2007 Feb 14. J Med Chem. 2007. PMID: 17298049
The synthesis and structure-activity relationship studies of selective acetyl-CoA carboxylase inhibitors containing 4-(thiazol-5-yl)but-3-yn-2-amino motif: polar region modifications.
Xu X, Weitzberg M, Keyes RF, Li Q, Wang R, Wang X, Zhang X, Frevert EU, Camp HS, Beutel BA, Sham HL, Gu YG. Xu X, et al. Among authors: keyes rf. Bioorg Med Chem Lett. 2007 Mar 15;17(6):1803-7. doi: 10.1016/j.bmcl.2006.12.047. Epub 2006 Dec 21. Bioorg Med Chem Lett. 2007. PMID: 17234407
An unusual intramolecular hetero-Diels-Alder cycloaddition.
Stoner EJ, Allen MS, Christesen AC, Henry RF, Hollis LS, Keyes R, Marsden I, Rehm TC, Shiroor SG, Soni NB, Stewart KD. Stoner EJ, et al. Among authors: keyes r. J Org Chem. 2005 Apr 15;70(8):3332-5. doi: 10.1021/jo0500131. J Org Chem. 2005. PMID: 15823010
21 results