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Recommendations for the introduction of metagenomic high-throughput sequencing in clinical virology, part I: Wet lab procedure.
López-Labrador FX, Brown JR, Fischer N, Harvala H, Van Boheemen S, Cinek O, Sayiner A, Madsen TV, Auvinen E, Kufner V, Huber M, Rodriguez C, Jonges M, Hönemann M, Susi P, Sousa H, Klapper PE, Pérez-Cataluňa A, Hernandez M, Molenkamp R, der Hoek LV, Schuurman R, Couto N, Leuzinger K, Simmonds P, Beer M, Höper D, Kamminga S, Feltkamp MCW, Rodríguez-Díaz J, Keyaerts E, Nielsen XC, Puchhammer-Stöckl E, Kroes ACM, Buesa J, Breuer J, Claas ECJ, de Vries JJC; ESCV Network on Next-Generation Sequencing. López-Labrador FX, et al. Among authors: keyaerts e. J Clin Virol. 2021 Jan;134:104691. doi: 10.1016/j.jcv.2020.104691. Epub 2020 Nov 18. J Clin Virol. 2021. PMID: 33278791 Free article.
Severity of COVID-19 among Hospitalized Patients: Omicron Remains a Severe Threat for Immunocompromised Hosts.
Nevejan L, Ombelet S, Laenen L, Keyaerts E, Demuyser T, Seyler L, Soetens O, Van Nedervelde E, Naesens R, Geysels D, Verstrepen W, Cattoir L, Martens S, Michel C, Mathieu E, Reynders M, Evenepoel A, Hellemans J, Vanhee M, Magerman K, Maes J, Matheeussen V, Boogaerts H, Lagrou K, Cuypers L, André E. Nevejan L, et al. Among authors: keyaerts e. Viruses. 2022 Dec 8;14(12):2736. doi: 10.3390/v14122736. Viruses. 2022. PMID: 36560741 Free PMC article.
Immunovirological and environmental screening reveals actionable risk factors for fatal COVID-19 during post-vaccination nursing home outbreaks.
Cuypers L, Keyaerts E, Hong SL, Gorissen S, Menezes SM, Starick M, Van Elslande J, Weemaes M, Wawina-Bokalanga T, Marti-Carreras J, Vanmechelen B, Van Holm B, Bloemen M, Dogne JM, Dufrasne F, Durkin K, Ruelle J, De Mendonca R, Wollants E, Vermeersch P; COVID-19 Genomics Belgium Consortium; Boulouffe C, Djiena A, Broucke C, Catry B, Lagrou K, Van Ranst M, Neyts J, Baele G, Maes P, André E, Dellicour S, Van Weyenbergh J. Cuypers L, et al. Among authors: keyaerts e. Nat Aging. 2023 Jun;3(6):722-733. doi: 10.1038/s43587-023-00421-1. Epub 2023 May 22. Nat Aging. 2023. PMID: 37217661 Free PMC article.
Benchmark of thirteen bioinformatic pipelines for metagenomic virus diagnostics using datasets from clinical samples.
de Vries JJC, Brown JR, Fischer N, Sidorov IA, Morfopoulou S, Huang J, Munnink BBO, Sayiner A, Bulgurcu A, Rodriguez C, Gricourt G, Keyaerts E, Beller L, Bachofen C, Kubacki J, Samuel C, Florian L, Dennis S, Beer M, Hoeper D, Huber M, Kufner V, Zaheri M, Lebrand A, Papa A, van Boheemen S, Kroes ACM, Breuer J, Lopez-Labrador FX, Claas ECJ. de Vries JJC, et al. Among authors: keyaerts e. J Clin Virol. 2021 Aug;141:104908. doi: 10.1016/j.jcv.2021.104908. Epub 2021 Jul 8. J Clin Virol. 2021. PMID: 34273858 Free PMC article.
Diagnostic accuracy of digital RNA quantification versus real-time PCR for the detection of respiratory syncytial virus in nasopharyngeal aspirates from children with acute respiratory infection.
Bouzas ML, Oliveira JR, Queiroz A, Fukutani KF, Barral A, Rector A, Wollants E, Keyaerts E, Van der Gucht W, Van Ranst M, Beuselinck K, de Oliveira CI, Van Weyenbergh J, Nascimento-Carvalho CM; Acute Respiratory Infection and Wheeze Study Group Phase I and II. Bouzas ML, et al. Among authors: keyaerts e. J Clin Virol. 2018 Sep;106:34-40. doi: 10.1016/j.jcv.2018.07.003. Epub 2018 Jul 19. J Clin Virol. 2018. PMID: 30031351
Nationwide quality assurance of high-throughput diagnostic molecular testing during the SARS-CoV-2 pandemic: role of the Belgian National Reference Centre.
Janssen R, Cuypers L, Laenen L, Keyaerts E, Beuselinck K, Janssenswillen S, Slechten B, Bode J, Wollants E, Van Laethem K, Rector A, Bloemen M, Sijmons A, de Schaetzen N, Capron A, Van Baelen K, Pascal T, Vermeiren C, Bureau F, Vandesompele J, De Smet P, Uten W, Malonne H, Kerkhofs P, De Cock J, Matheeussen V, Verhasselt B, Gillet L, Detry G, Bearzatto B, Degosserie J, Henin C, Pairoux G; COVID-19 Genomics Belgium Consortium; Maes P, Van Ranst M, Lagrou K, Dequeker E, André E. Janssen R, et al. Among authors: keyaerts e. Virol J. 2024 Feb 10;21(1):40. doi: 10.1186/s12985-024-02308-y. Virol J. 2024. PMID: 38341597 Free PMC article. Review.
47 results