Key J - Search Results

1

Mid-Gestation lethality of Atxn2l-Ablated Mice.

Key J, Harter PN, Sen NE, Gradhand E, Auburger G, Gispert S. Key J, et al. Int J Mol Sci. 2020 Jul 20;21(14):5124. doi: 10.3390/ijms21145124. Int J Mol Sci. 2020. PMID: 32698485 Free PMC article.

2

Progression of pathology in PINK1-deficient mouse brain from splicing via ubiquitination, ER stress, and mitophagy changes to neuroinflammation.

Torres-Odio S, Key J, Hoepken HH, Canet-Pons J, Valek L, Roller B, Walter M, Morales-Gordo B, Meierhofer D, Harter PN, Mittelbronn M, Tegeder I, Gispert S, Auburger G. Torres-Odio S, et al. Among authors: key j. J Neuroinflammation. 2017 Aug 2;14(1):154. doi: 10.1186/s12974-017-0928-0. J Neuroinflammation. 2017. PMID: 28768533 Free PMC article.

3

Ubiquitylome profiling of Parkin-null brain reveals dysregulation of calcium homeostasis factors ATP1A2, Hippocalcin and GNA11, reflected by altered firing of noradrenergic neurons.

Key J, Mueller AK, Gispert S, Matschke L, Wittig I, Corti O, Münch C, Decher N, Auburger G. Key J, et al. Neurobiol Dis. 2019 Jul;127:114-130. doi: 10.1016/j.nbd.2019.02.008. Epub 2019 Feb 11. Neurobiol Dis. 2019. PMID: 30763678

4

SerThr-PhosphoProteome of Brain from Aged PINK1-KO+A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes.

Auburger G, Gispert S, Torres-Odio S, Jendrach M, Brehm N, Canet-Pons J, Key J, Sen NE. Auburger G, et al. Among authors: key j. Int J Mol Sci. 2019 Jul 4;20(13):3284. doi: 10.3390/ijms20133284. Int J Mol Sci. 2019. PMID: 31277379 Free PMC article.

5

Global Proteome of LonP1^+/- Mouse Embryonal Fibroblasts Reveals Impact on Respiratory Chain, but No Interdependence between Eral1 and Mitoribosomes.

Key J, Kohli A, Bárcena C, López-Otín C, Heidler J, Wittig I, Auburger G. Key J, et al. Int J Mol Sci. 2019 Sep 12;20(18):4523. doi: 10.3390/ijms20184523. Int J Mol Sci. 2019. PMID: 31547314 Free PMC article.

6

Loss of mitochondrial ClpP, Lonp1, and Tfam triggers transcriptional induction of Rnf213, a susceptibility factor for moyamoya disease.

Key J, Maletzko A, Kohli A, Gispert S, Torres-Odio S, Wittig I, Heidler J, Bárcena C, López-Otín C, Lei Y, West AP, Münch C, Auburger G. Key J, et al. Neurogenetics. 2020 Jul;21(3):187-203. doi: 10.1007/s10048-020-00609-2. Epub 2020 Apr 28. Neurogenetics. 2020. PMID: 32342250 Free PMC article.

7

Systematic Surveys of Iron Homeostasis Mechanisms Reveal Ferritin Superfamily and Nucleotide Surveillance Regulation to be Modified by PINK1 Absence.

Key J, Sen NE, Arsović A, Krämer S, Hülse R, Khan NN, Meierhofer D, Gispert S, Koepf G, Auburger G. Key J, et al. Cells. 2020 Oct 2;9(10):2229. doi: 10.3390/cells9102229. Cells. 2020. PMID: 33023155 Free PMC article.

8

Atxn2-CAG100-KnockIn mouse spinal cord shows progressive TDP43 pathology associated with cholesterol biosynthesis suppression.

Canet-Pons J, Sen NE, Arsović A, Almaguer-Mederos LE, Halbach MV, Key J, Döring C, Kerksiek A, Picchiarelli G, Cassel R, René F, Dieterlé S, Fuchs NV, König R, Dupuis L, Lütjohann D, Gispert S, Auburger G. Canet-Pons J, et al. Among authors: key j. Neurobiol Dis. 2021 May;152:105289. doi: 10.1016/j.nbd.2021.105289. Epub 2021 Feb 10. Neurobiol Dis. 2021. PMID: 33577922 Free article.

9

Loss of Mitochondrial Protease CLPP Activates Type I IFN Responses through the Mitochondrial DNA-cGAS-STING Signaling Axis.

Torres-Odio S, Lei Y, Gispert S, Maletzko A, Key J, Menissy SS, Wittig I, Auburger G, West AP. Torres-Odio S, et al. Among authors: key j. J Immunol. 2021 Apr 15;206(8):1890-1900. doi: 10.4049/jimmunol.2001016. Epub 2021 Mar 17. J Immunol. 2021. PMID: 33731338 Free PMC article.

10

Increased presence of nuclear DNAJA3 and upregulation of cytosolic STAT1 and of nucleic acid sensors trigger innate immunity in the ClpP-null mouse.

Maletzko A, Key J, Wittig I, Gispert S, Koepf G, Canet-Pons J, Torres-Odio S, West AP, Auburger G. Maletzko A, et al. Among authors: key j. Neurogenetics. 2021 Oct;22(4):297-312. doi: 10.1007/s10048-021-00657-2. Epub 2021 Aug 3. Neurogenetics. 2021. PMID: 34345994 Free PMC article.

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