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Discovery of G Protein-Biased Antagonists against 5-HT7R.
Kwag R, Lee J, Kim D, Lee H, Yeom M, Woo J, Cho Y, Kim HJ, Kim J, Keum G, Jeon B, Choo H. Kwag R, et al. Among authors: keum g. J Med Chem. 2021 Sep 23;64(18):13766-13779. doi: 10.1021/acs.jmedchem.1c01093. Epub 2021 Sep 14. J Med Chem. 2021. PMID: 34519505
Aryl biphenyl-3-ylmethylpiperazines as 5-HT7 receptor antagonists.
Kim J, Kim Y, Tae J, Yeom M, Moon B, Huang XP, Roth BL, Lee K, Rhim H, Choo IH, Chong Y, Keum G, Nam G, Choo H. Kim J, et al. Among authors: keum g. ChemMedChem. 2013 Nov;8(11):1855-64. doi: 10.1002/cmdc.201300240. Epub 2013 Sep 3. ChemMedChem. 2013. PMID: 24039134
Synthesis and biological evaluation of 1-(isoxazol-5-ylmethylaminoethyl)-4-phenyl tetrahydropyridine and piperidine derivatives as potent T-type calcium channel blockers with antinociceptive effect in a neuropathic pain model.
Lee JH, Seo SH, Lim EJ, Cho NC, Nam G, Kang SB, Pae AN, Jeong N, Keum G. Lee JH, et al. Among authors: keum g. Eur J Med Chem. 2014 Mar 3;74:246-57. doi: 10.1016/j.ejmech.2013.12.056. Epub 2014 Jan 8. Eur J Med Chem. 2014. PMID: 24480356
Novel thienopyrimidinones as mGluR1 antagonists.
Kim Y, Kim J, Kim S, Ki Y, Seo SH, Tae J, Ko MK, Jang HS, Lim EJ, Song C, Cho Y, Koh HY, Chong Y, Choo IH, Keum G, Min SJ, Choo H. Kim Y, et al. Among authors: keum g. Eur J Med Chem. 2014 Oct 6;85:629-37. doi: 10.1016/j.ejmech.2014.08.027. Epub 2014 Aug 8. Eur J Med Chem. 2014. PMID: 25127154
Synthesis and in vitro evaluation of the antitubercular and antibacterial activity of novel oxazolidinones bearing octahydrocyclopenta[c]pyrrol-2-yl moieties.
Bhattarai D, Lee JH, Seo SH, Nam G, Choo H, Kang SB, Kwak JH, Oh T, Cho SN, Pae AN, Kim EE, Jeong N, Keum G. Bhattarai D, et al. Among authors: keum g. Chem Pharm Bull (Tokyo). 2014;62(12):1214-24. doi: 10.1248/cpb.c14-00510. Epub 2014 Oct 9. Chem Pharm Bull (Tokyo). 2014. PMID: 25297523 Free article.
82 results