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Sphingolipid metabolism determines the therapeutic efficacy of nanoliposomal ceramide in acute myeloid leukemia.
Barth BM, Wang W, Toran PT, Fox TE, Annageldiyev C, Ondrasik RM, Keasey NR, Brown TJ, Devine VG, Sullivan EC, Cote AL, Papakotsi V, Tan SF, Shanmugavelandy SS, Deering TG, Needle DB, Stern ST, Zhu J, Liao J, Viny AD, Feith DJ, Levine RL, Wang HG, Loughran TP Jr, Sharma A, Kester M, Claxton DF. Barth BM, et al. Among authors: kester m. Blood Adv. 2019 Sep 10;3(17):2598-2603. doi: 10.1182/bloodadvances.2018021295. Blood Adv. 2019. PMID: 31488436 Free PMC article.
Targeting of survivin by nanoliposomal ceramide induces complete remission in a rat model of NK-LGL leukemia.
Liu X, Ryland L, Yang J, Liao A, Aliaga C, Watts R, Tan SF, Kaiser J, Shanmugavelandy SS, Rogers A, Loughran K, Petersen B, Yuen J, Meng F, Baab KT, Jarbadan NR, Broeg K, Zhang R, Liao J, Sayers TJ, Kester M, Loughran TP Jr. Liu X, et al. Among authors: kester m. Blood. 2010 Nov 18;116(20):4192-201. doi: 10.1182/blood-2010-02-271080. Epub 2010 Jul 29. Blood. 2010. PMID: 20671121 Free PMC article.
Dysregulation of sphingolipid metabolism in cancer.
Ryland LK, Fox TE, Liu X, Loughran TP, Kester M. Ryland LK, et al. Among authors: kester m. Cancer Biol Ther. 2011 Jan 15;11(2):138-49. doi: 10.4161/cbt.11.2.14624. Epub 2011 Jan 15. Cancer Biol Ther. 2011. PMID: 21209555 Review.
Ceramide-based therapeutics for the treatment of cancer.
Barth BM, Cabot MC, Kester M. Barth BM, et al. Among authors: kester m. Anticancer Agents Med Chem. 2011 Nov;11(9):911-9. doi: 10.2174/187152011797655177. Anticancer Agents Med Chem. 2011. PMID: 21707481 Review.
Therapeutic efficacy of FTY720 in a rat model of NK-cell leukemia.
Liao A, Broeg K, Fox T, Tan SF, Watters R, Shah MV, Zhang LQ, Li Y, Ryland L, Yang J, Aliaga C, Dewey A, Rogers A, Loughran K, Hirsch L, Jarbadan NR, Baab KT, Liao J, Wang HG, Kester M, Desai D, Amin S, Loughran TP Jr, Liu X. Liao A, et al. Among authors: kester m. Blood. 2011 Sep 8;118(10):2793-800. doi: 10.1182/blood-2011-01-331447. Epub 2011 Jul 18. Blood. 2011. PMID: 21768294 Free PMC article.
Combinatorial therapies improve the therapeutic efficacy of nanoliposomal ceramide for pancreatic cancer.
Jiang Y, DiVittore NA, Kaiser JM, Shanmugavelandy SS, Fritz JL, Heakal Y, Tagaram HR, Cheng H, Cabot MC, Staveley-O'Carroll KF, Tran MA, Fox TE, Barth BM, Kester M. Jiang Y, et al. Among authors: kester m. Cancer Biol Ther. 2011 Oct 1;12(7):574-85. doi: 10.4161/cbt.12.7.15971. Epub 2011 Oct 1. Cancer Biol Ther. 2011. PMID: 21795855 Free PMC article.
Modification of sphingolipid metabolism by tamoxifen and N-desmethyltamoxifen in acute myelogenous leukemia--Impact on enzyme activity and response to cytotoxics.
Morad SA, Tan SF, Feith DJ, Kester M, Claxton DF, Loughran TP Jr, Barth BM, Fox TE, Cabot MC. Morad SA, et al. Among authors: kester m. Biochim Biophys Acta. 2015 Jul;1851(7):919-28. doi: 10.1016/j.bbalip.2015.03.001. Epub 2015 Mar 10. Biochim Biophys Acta. 2015. PMID: 25769964 Free PMC article.
Ceramide-tamoxifen regimen targets bioenergetic elements in acute myelogenous leukemia.
Morad SA, Ryan TE, Neufer PD, Zeczycki TN, Davis TS, MacDougall MR, Fox TE, Tan SF, Feith DJ, Loughran TP Jr, Kester M, Claxton DF, Barth BM, Deering TG, Cabot MC. Morad SA, et al. Among authors: kester m. J Lipid Res. 2016 Jul;57(7):1231-42. doi: 10.1194/jlr.M067389. Epub 2016 May 2. J Lipid Res. 2016. PMID: 27140664 Free PMC article.
467 results