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Synergistic combination therapy with nanoliposomal C6-ceramide and vinblastine is associated with autophagy dysfunction in hepatocarcinoma and colorectal cancer models.
Adiseshaiah PP, Clogston JD, McLeland CB, Rodriguez J, Potter TM, Neun BW, Skoczen SL, Shanmugavelandy SS, Kester M, Stern ST, McNeil SE. Adiseshaiah PP, et al. Among authors: kester m. Cancer Lett. 2013 Sep 1;337(2):254-65. doi: 10.1016/j.canlet.2013.04.034. Epub 2013 May 7. Cancer Lett. 2013. PMID: 23664889 Free PMC article.
Combinatorial therapies improve the therapeutic efficacy of nanoliposomal ceramide for pancreatic cancer.
Jiang Y, DiVittore NA, Kaiser JM, Shanmugavelandy SS, Fritz JL, Heakal Y, Tagaram HR, Cheng H, Cabot MC, Staveley-O'Carroll KF, Tran MA, Fox TE, Barth BM, Kester M. Jiang Y, et al. Among authors: kester m. Cancer Biol Ther. 2011 Oct 1;12(7):574-85. doi: 10.4161/cbt.12.7.15971. Epub 2011 Oct 1. Cancer Biol Ther. 2011. PMID: 21795855 Free PMC article.
Sphingolipid metabolism determines the therapeutic efficacy of nanoliposomal ceramide in acute myeloid leukemia.
Barth BM, Wang W, Toran PT, Fox TE, Annageldiyev C, Ondrasik RM, Keasey NR, Brown TJ, Devine VG, Sullivan EC, Cote AL, Papakotsi V, Tan SF, Shanmugavelandy SS, Deering TG, Needle DB, Stern ST, Zhu J, Liao J, Viny AD, Feith DJ, Levine RL, Wang HG, Loughran TP Jr, Sharma A, Kester M, Claxton DF. Barth BM, et al. Among authors: kester m. Blood Adv. 2019 Sep 10;3(17):2598-2603. doi: 10.1182/bloodadvances.2018021295. Blood Adv. 2019. PMID: 31488436 Free PMC article.
C6-ceramide nanoliposomes target the Warburg effect in chronic lymphocytic leukemia.
Ryland LK, Doshi UA, Shanmugavelandy SS, Fox TE, Aliaga C, Broeg K, Baab KT, Young M, Khan O, Haakenson JK, Jarbadan NR, Liao J, Wang HG, Feith DJ, Loughran TP Jr, Liu X, Kester M. Ryland LK, et al. Among authors: kester m. PLoS One. 2013 Dec 19;8(12):e84648. doi: 10.1371/journal.pone.0084648. eCollection 2013. PLoS One. 2013. PMID: 24367685 Free PMC article.
Inhibition of NADPH oxidase by glucosylceramide confers chemoresistance.
Barth BM, Gustafson SJ, Young MM, Fox TE, Shanmugavelandy SS, Kaiser JM, Cabot MC, Kester M, Kuhn TB. Barth BM, et al. Among authors: kester m. Cancer Biol Ther. 2010 Dec 1;10(11):1126-36. doi: 10.4161/cbt.10.11.13438. Epub 2010 Dec 1. Cancer Biol Ther. 2010. PMID: 20935456 Free PMC article.
467 results