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Regulatory T cell abundance and activation status before and after priming with HIVIS-DNA and boosting with MVA-HIV/rgp140/GLA-AF may impact the magnitude of the vaccine-induced immune responses.
Chissumba RM, Luciano A, Namalango E, Bauer A, Bhatt N, Wahren B, Nilsson C, Geldmacher C, Scarlatti G, Jani I, Kestens L; TaMoVac II group. Chissumba RM, et al. Among authors: kestens l. Immunobiology. 2018 Dec;223(12):792-801. doi: 10.1016/j.imbio.2018.08.006. Epub 2018 Aug 12. Immunobiology. 2018. PMID: 30121146 Clinical Trial.
Helios expressing regulatory T cells are correlated with decreased IL-2 producing CD8 T cells and antibody diversity in Mozambican individuals living chronically with HIV-1.
Matavele Chissumba R, Magul C, Macamo R, Monteiro V, Enosse M, Macicame I, Cumbane V, Bhatt N, Viegas E, Imbach M, Eller LA, Polyak CS, Kestens L; RV363 Study Group. Matavele Chissumba R, et al. Among authors: kestens l. BMC Immunol. 2022 Mar 14;23(1):12. doi: 10.1186/s12865-022-00487-3. BMC Immunol. 2022. PMID: 35287587 Free PMC article.
Lower Pre-Treatment T Cell Activation in Early- and Late-Onset Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome.
Goovaerts O, Jennes W, Massinga-Loembé M, Ondoa P, Ceulemans A, Vereecken C, Worodria W, Mayanja-Kizza H, Colebunders R, Kestens L; TB-IRIS Study Group. Goovaerts O, et al. Among authors: kestens l. PLoS One. 2015 Jul 24;10(7):e0133924. doi: 10.1371/journal.pone.0133924. eCollection 2015. PLoS One. 2015. PMID: 26208109 Free PMC article.
193 results