Kerwin SM - Search Results

1

Synthesis and docking studies of novel antitumor benzimidazoles.

Omar MA, Shaker YM, Galal SA, Ali MM, Kerwin SM, Li J, Tokuda H, Ramadan RA, El Diwani HI. Omar MA, et al. Among authors: kerwin sm. Bioorg Med Chem. 2012 Dec 15;20(24):6989-7001. doi: 10.1016/j.bmc.2012.10.010. Epub 2012 Oct 16. Bioorg Med Chem. 2012. PMID: 23123017

2

New transition metal ion complexes with benzimidazole-5-carboxylic acid hydrazides with antitumor activity.

Galal SA, Hegab KH, Kassab AS, Rodriguez ML, Kerwin SM, el-Khamry AM, el-Diwani HI. Galal SA, et al. Among authors: kerwin sm. Eur J Med Chem. 2009 Apr;44(4):1500-8. doi: 10.1016/j.ejmech.2008.07.013. Epub 2008 Jul 19. Eur J Med Chem. 2009. PMID: 18752870

3

Cytotoxic 1,2-dialkynylimidazole-based aza-enediynes: aza-Bergman rearrangement rates do not predict cytotoxicity.

Laroche C, Li J, Kerwin SM. Laroche C, et al. Among authors: kerwin sm. J Med Chem. 2011 Jul 28;54(14):5059-69. doi: 10.1021/jm200289j. Epub 2011 Jun 28. J Med Chem. 2011. PMID: 21667990

4

Synthesis and biological evaluation of p38alpha kinase-targeting dialkynylimidazoles.

Li J, Kaoud TS, Laroche C, Dalby KN, Kerwin SM. Li J, et al. Among authors: kerwin sm. Bioorg Med Chem Lett. 2009 Nov 15;19(22):6293-7. doi: 10.1016/j.bmcl.2009.09.094. Epub 2009 Sep 27. Bioorg Med Chem Lett. 2009. PMID: 19822424 Free PMC article.

5

Synthesis and evaluation of anticancer benzoxazoles and benzimidazoles related to UK-1.

Kumar D, Jacob MR, Reynolds MB, Kerwin SM. Kumar D, et al. Among authors: kerwin sm. Bioorg Med Chem. 2002 Dec;10(12):3997-4004. doi: 10.1016/s0968-0896(02)00327-9. Bioorg Med Chem. 2002. PMID: 12413851

6

Coupling reactions of bromoalkynes with imidazoles mediated by copper salts: synthesis of novel N-alkynylimidazoles.

Laroche C, Li J, Freyer MW, Kerwin SM. Laroche C, et al. Among authors: kerwin sm. J Org Chem. 2008 Aug 15;73(16):6462-5. doi: 10.1021/jo801118q. Epub 2008 Jul 23. J Org Chem. 2008. PMID: 18646827

7

Cyclization kinetics and biological evaluation of an anticancer 1,2-dialkynylimidazole.

Laroche C, Li J, Gonzales C, David WM, Kerwin SM. Laroche C, et al. Among authors: kerwin sm. Org Biomol Chem. 2010 Apr 7;8(7):1535-9. doi: 10.1039/b925261d. Epub 2010 Feb 15. Org Biomol Chem. 2010. PMID: 20237664

8

Synthesis, metal ion binding, and biological evaluation of new anticancer 2-(2'-hydroxyphenyl)benzoxazole analogs of UK-1.

McKee ML, Kerwin SM. McKee ML, et al. Among authors: kerwin sm. Bioorg Med Chem. 2008 Feb 15;16(4):1775-83. doi: 10.1016/j.bmc.2007.11.019. Epub 2007 Nov 12. Bioorg Med Chem. 2008. PMID: 18037301 Free PMC article.

9

Synthesis, DNA cleavage, and cytotoxicity of a series of bis(propargylic) sulfone crown ethers.

McPhee MM, Kerwin SM. McPhee MM, et al. Among authors: kerwin sm. Bioorg Med Chem. 2001 Nov;9(11):2809-18. doi: 10.1016/s0968-0896(01)00150-x. Bioorg Med Chem. 2001. PMID: 11597461

10

N-propargyl-2-alkynylbenzothiazolium aza-enediynes: role of the 2-alkynylbenzothiazolium functionality in DNA cleavage.

Kumar D, David WM, Kerwin SM. Kumar D, et al. Among authors: kerwin sm. Bioorg Med Chem Lett. 2001 Nov 19;11(22):2971-4. doi: 10.1016/s0960-894x(01)00606-0. Bioorg Med Chem Lett. 2001. PMID: 11677138

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