Kershaw NJ - Search Results

1

The molecular details of cytokine signaling via the JAK/STAT pathway.

Morris R, Kershaw NJ, Babon JJ. Morris R, et al. Among authors: kershaw nj. Protein Sci. 2018 Dec;27(12):1984-2009. doi: 10.1002/pro.3519. Protein Sci. 2018. PMID: 30267440 Free PMC article. Review.

2

Suppression of cytokine signaling by SOCS3: characterization of the mode of inhibition and the basis of its specificity.

Babon JJ, Kershaw NJ, Murphy JM, Varghese LN, Laktyushin A, Young SN, Lucet IS, Norton RS, Nicola NA. Babon JJ, et al. Among authors: kershaw nj. Immunity. 2012 Feb 24;36(2):239-50. doi: 10.1016/j.immuni.2011.12.015. Immunity. 2012. PMID: 22342841 Free PMC article.

3

In vitro ubiquitination of cytokine signaling components.

Babon JJ, Laktyushin A, Kershaw NJ. Babon JJ, et al. Among authors: kershaw nj. Methods Mol Biol. 2013;967:261-71. doi: 10.1007/978-1-62703-242-1_19. Methods Mol Biol. 2013. PMID: 23296736

4

SOCS3 binds specific receptor-JAK complexes to control cytokine signaling by direct kinase inhibition.

Kershaw NJ, Murphy JM, Liau NP, Varghese LN, Laktyushin A, Whitlock EL, Lucet IS, Nicola NA, Babon JJ. Kershaw NJ, et al. Nat Struct Mol Biol. 2013 Apr;20(4):469-76. doi: 10.1038/nsmb.2519. Epub 2013 Mar 3. Nat Struct Mol Biol. 2013. PMID: 23454976 Free PMC article.

5

Molecular architecture of the ankyrin SOCS box family of Cul5-dependent E3 ubiquitin ligases.

Muniz JR, Guo K, Kershaw NJ, Ayinampudi V, von Delft F, Babon JJ, Bullock AN. Muniz JR, et al. Among authors: kershaw nj. J Mol Biol. 2013 Sep 9;425(17):3166-77. doi: 10.1016/j.jmb.2013.06.015. Epub 2013 Jun 25. J Mol Biol. 2013. PMID: 23806657 Free PMC article.

6

Regulation of Janus kinases by SOCS proteins.

Kershaw NJ, Murphy JM, Lucet IS, Nicola NA, Babon JJ. Kershaw NJ, et al. Biochem Soc Trans. 2013 Aug;41(4):1042-7. doi: 10.1042/BST20130077. Biochem Soc Trans. 2013. PMID: 23863176 Free PMC article. Review.

7

Crystal structure of the TRIM25 B30.2 (PRYSPRY) domain: a key component of antiviral signalling.

D'Cruz AA, Kershaw NJ, Chiang JJ, Wang MK, Nicola NA, Babon JJ, Gack MU, Nicholson SE. D'Cruz AA, et al. Among authors: kershaw nj. Biochem J. 2013 Dec 1;456(2):231-40. doi: 10.1042/BJ20121425. Biochem J. 2013. PMID: 24015671 Free PMC article.

8

Reconstruction of an active SOCS3-based E3 ubiquitin ligase complex in vitro: identification of the active components and JAK2 and gp130 as substrates.

Kershaw NJ, Laktyushin A, Nicola NA, Babon JJ. Kershaw NJ, et al. Growth Factors. 2014 Feb;32(1):1-10. doi: 10.3109/08977194.2013.877005. Epub 2014 Jan 20. Growth Factors. 2014. PMID: 24438103 Free PMC article.

9

Roquin binds microRNA-146a and Argonaute2 to regulate microRNA homeostasis.

Srivastava M, Duan G, Kershaw NJ, Athanasopoulos V, Yeo JH, Ose T, Hu D, Brown SH, Jergic S, Patel HR, Pratama A, Richards S, Verma A, Jones EY, Heissmeyer V, Preiss T, Dixon NE, Chong MM, Babon JJ, Vinuesa CG. Srivastava M, et al. Among authors: kershaw nj. Nat Commun. 2015 Feb 20;6:6253. doi: 10.1038/ncomms7253. Nat Commun. 2015. PMID: 25697406 Free PMC article.

10

VHL: Cullin-g the hypoxic response.

Kershaw NJ, Babon JJ. Kershaw NJ, et al. Structure. 2015 Mar 3;23(3):435-436. doi: 10.1016/j.str.2015.02.003. Structure. 2015. PMID: 25738382 Free article.

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