Kerschner JL - Search Results

1

Early developmental phenotypes in the cystic fibrosis sheep model.

Van Wettere AJ, Leir SH, Cotton CU, Regouski M, Viotti Perisse I, Kerschner JL, Paranjapye A, Fan Z, Liu Y, Schacht M, White KL, Polejaeva IA, Harris A. Van Wettere AJ, et al. Among authors: kerschner jl. FASEB Bioadv. 2022 Oct 31;5(1):13-26. doi: 10.1096/fba.2022-00085. eCollection 2023 Jan. FASEB Bioadv. 2022. PMID: 36643895 Free PMC article.

2

Intronic enhancers coordinate epithelial-specific looping of the active CFTR locus.

Ott CJ, Blackledge NP, Kerschner JL, Leir SH, Crawford GE, Cotton CU, Harris A. Ott CJ, et al. Among authors: kerschner jl. Proc Natl Acad Sci U S A. 2009 Nov 24;106(47):19934-9. doi: 10.1073/pnas.0900946106. Epub 2009 Nov 6. Proc Natl Acad Sci U S A. 2009. PMID: 19897727 Free PMC article.

3

Transcriptional networks driving enhancer function in the CFTR gene.

Kerschner JL, Harris A. Kerschner JL, et al. Biochem J. 2012 Sep 1;446(2):203-12. doi: 10.1042/BJ20120693. Biochem J. 2012. PMID: 22671145 Free PMC article.

4

Nucleosome mapping across the CFTR locus identifies novel regulatory factors.

Yigit E, Bischof JM, Zhang Z, Ott CJ, Kerschner JL, Leir SH, Buitrago-Delgado E, Zhang Q, Wang JP, Widom J, Harris A. Yigit E, et al. Among authors: kerschner jl. Nucleic Acids Res. 2013 Mar 1;41(5):2857-68. doi: 10.1093/nar/gks1462. Epub 2013 Jan 15. Nucleic Acids Res. 2013. PMID: 23325854 Free PMC article.

5

Chromatin remodeling mediated by the FOXA1/A2 transcription factors activates CFTR expression in intestinal epithelial cells.

Kerschner JL, Gosalia N, Leir SH, Harris A. Kerschner JL, et al. Epigenetics. 2014 Apr;9(4):557-65. doi: 10.4161/epi.27696. Epub 2014 Jan 17. Epigenetics. 2014. PMID: 24440874 Free PMC article.

6

Architectural proteins CTCF and cohesin have distinct roles in modulating the higher order structure and expression of the CFTR locus.

Gosalia N, Neems D, Kerschner JL, Kosak ST, Harris A. Gosalia N, et al. Among authors: kerschner jl. Nucleic Acids Res. 2014 Sep;42(15):9612-22. doi: 10.1093/nar/gku648. Epub 2014 Jul 31. Nucleic Acids Res. 2014. PMID: 25081205 Free PMC article.

7

FOXA2 regulates a network of genes involved in critical functions of human intestinal epithelial cells.

Gosalia N, Yang R, Kerschner JL, Harris A. Gosalia N, et al. Among authors: kerschner jl. Physiol Genomics. 2015 Jul;47(7):290-7. doi: 10.1152/physiolgenomics.00024.2015. Epub 2015 Apr 28. Physiol Genomics. 2015. PMID: 25921584 Free PMC article.

8

Differential contribution of cis-regulatory elements to higher order chromatin structure and expression of the CFTR locus.

Yang R, Kerschner JL, Gosalia N, Neems D, Gorsic LK, Safi A, Crawford GE, Kosak ST, Leir SH, Harris A. Yang R, et al. Among authors: kerschner jl. Nucleic Acids Res. 2016 Apr 20;44(7):3082-94. doi: 10.1093/nar/gkv1358. Epub 2015 Dec 15. Nucleic Acids Res. 2016. PMID: 26673704 Free PMC article.

9

Hepatocyte nuclear factor 1 coordinates multiple processes in a model of intestinal epithelial cell function.

Yang R, Kerschner JL, Harris A. Yang R, et al. Among authors: kerschner jl. Biochim Biophys Acta. 2016 Apr;1859(4):591-8. doi: 10.1016/j.bbagrm.2016.02.005. Epub 2016 Feb 6. Biochim Biophys Acta. 2016. PMID: 26855178 Free PMC article.

10

Regulatory dynamics of 11p13 suggest a role for EHF in modifying CF lung disease severity.

Stolzenburg LR, Yang R, Kerschner JL, Fossum S, Xu M, Hoffmann A, Lamar KM, Ghosh S, Wachtel S, Leir SH, Harris A. Stolzenburg LR, et al. Among authors: kerschner jl. Nucleic Acids Res. 2017 Sep 6;45(15):8773-8784. doi: 10.1093/nar/gkx482. Nucleic Acids Res. 2017. PMID: 28549169 Free PMC article.

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