Kerrigan JE - Search Results

1

A G-quadruplex stabilizer induces M-phase cell cycle arrest.

Tsai YC, Qi H, Lin CP, Lin RK, Kerrigan JE, Rzuczek SG, LaVoie EJ, Rice JE, Pilch DS, Lyu YL, Liu LF. Tsai YC, et al. Among authors: kerrigan je. J Biol Chem. 2009 Aug 21;284(34):22535-43. doi: 10.1074/jbc.M109.020230. Epub 2009 Jun 16. J Biol Chem. 2009. PMID: 19531483 Free PMC article.

2

Dietary isothiocyanate-induced apoptosis via thiol modification of DNA topoisomerase IIα.

Lin RK, Zhou N, Lyu YL, Tsai YC, Lu CH, Kerrigan J, Chen YT, Guan Z, Hsieh TS, Liu LF. Lin RK, et al. J Biol Chem. 2011 Sep 23;286(38):33591-600. doi: 10.1074/jbc.M111.258137. Epub 2011 Aug 1. J Biol Chem. 2011. PMID: 21828038 Free PMC article.

3

Synthesis and G-quadruplex stabilizing properties of a series of oxazole-containing macrocycles.

Minhas GS, Pilch DS, Kerrigan JE, LaVoie EJ, Rice JE. Minhas GS, et al. Among authors: kerrigan je. Bioorg Med Chem Lett. 2006 Aug 1;16(15):3891-5. doi: 10.1016/j.bmcl.2006.05.038. Epub 2006 Jun 2. Bioorg Med Chem Lett. 2006. PMID: 16735121

4

5H-8,9-dimethoxy-5-(2-N,N-dimethylaminoethyl)dibenzo[c,h][1,6]naphthyridin-6-ones and related compounds as TOP1-targeting agents: influence of structure on the ternary cleavable complex formation.

Kerrigan JE, Pilch DS, Ruchelman AL, Zhou N, Liu A, Liu L, LaVoie EJ. Kerrigan JE, et al. Bioorg Med Chem Lett. 2003 Oct 20;13(20):3395-9. doi: 10.1016/s0960-894x(03)00797-2. Bioorg Med Chem Lett. 2003. PMID: 14505635

5

Nitro and amino substitution within the A-ring of 5H-8,9-dimethoxy-5-(2-N,N-dimethylaminoethyl)dibenzo[c,h][1,6]naphthyridin-6-ones: influence on topoisomerase I-targeting activity and cytotoxicity.

Ruchelman AL, Kerrigan JE, Li TK, Zhou N, Liu A, Liu LF, LaVoie EJ. Ruchelman AL, et al. Among authors: kerrigan je. Bioorg Med Chem. 2004 Jul 1;12(13):3731-42. doi: 10.1016/j.bmc.2004.03.076. Bioorg Med Chem. 2004. PMID: 15186859

6

A bactericidal guanidinomethyl biaryl that alters the dynamics of bacterial FtsZ polymerization.

Kaul M, Parhi AK, Zhang Y, LaVoie EJ, Tuske S, Arnold E, Kerrigan JE, Pilch DS. Kaul M, et al. Among authors: kerrigan je. J Med Chem. 2012 Nov 26;55(22):10160-76. doi: 10.1021/jm3012728. Epub 2012 Oct 26. J Med Chem. 2012. PMID: 23050700 Free PMC article.

7

Topoisomerase IIbeta mediated DNA double-strand breaks: implications in doxorubicin cardiotoxicity and prevention by dexrazoxane.

Lyu YL, Kerrigan JE, Lin CP, Azarova AM, Tsai YC, Ban Y, Liu LF. Lyu YL, et al. Among authors: kerrigan je. Cancer Res. 2007 Sep 15;67(18):8839-46. doi: 10.1158/0008-5472.CAN-07-1649. Cancer Res. 2007. PMID: 17875725

8

Enterococcal and streptococcal resistance to PC190723 and related compounds: molecular insights from a FtsZ mutational analysis.

Kaul M, Zhang Y, Parhi AK, Lavoie EJ, Tuske S, Arnold E, Kerrigan JE, Pilch DS. Kaul M, et al. Among authors: kerrigan je. Biochimie. 2013 Oct;95(10):1880-7. doi: 10.1016/j.biochi.2013.06.010. Epub 2013 Jun 25. Biochimie. 2013. PMID: 23806423 Free PMC article.

9

A structural model for the ternary cleavable complex formed between human topoisomerase I, DNA, and camptothecin.

Kerrigan JE, Pilch DS. Kerrigan JE, et al. Biochemistry. 2001 Aug 21;40(33):9792-8. doi: 10.1021/bi010913l. Biochemistry. 2001. PMID: 11502172

10

Thermodynamics of aminoglycoside-rRNA recognition.

Pilch DS, Kaul M, Barbieri CM, Kerrigan JE. Pilch DS, et al. Among authors: kerrigan je. Biopolymers. 2003 Sep;70(1):58-79. doi: 10.1002/bip.10411. Biopolymers. 2003. PMID: 12925993 Review.

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