Kerr WG - Search Results

1

SHIP inhibition mediates select TREM2-induced microglial functions.

Ramakrishnan GS, Berry WL, Pacherille A, Kerr WG, Chisholm JD, Pedicone C, Humphrey MB. Ramakrishnan GS, et al. Among authors: kerr wg. Mol Immunol. 2024 Jun;170:35-45. doi: 10.1016/j.molimm.2024.04.002. Epub 2024 Apr 12. Mol Immunol. 2024. PMID: 38613944 Free article.

2

AI is a viable alternative to high throughput screening: a 318-target study.

Atomwise AIMS Program. Atomwise AIMS Program. Sci Rep. 2024 Apr 2;14(1):7526. doi: 10.1038/s41598-024-54655-z. Sci Rep. 2024. PMID: 38565852 Free PMC article.

3

Structure-Activity Studies on Bis-Sulfonamide SHIP1 Activators.

Meyer ST, Fernandes S, Anderson RE, Pacherille A, Toms B, Kerr WG, Chisholm JD. Meyer ST, et al. Among authors: kerr wg. Molecules. 2023 Dec 12;28(24):8048. doi: 10.3390/molecules28248048. Molecules. 2023. PMID: 38138538 Free PMC article.

4

SHIP1 inhibition via 3-alpha-amino-cholestane enhances protection against Leishmania infection.

Chowdhury BP, Das S, Bodhale N, Prakash Pandey S, Sudan R, Srivastava N, Chisholm JD, Kerr WG, Majumdar S, Saha B. Chowdhury BP, et al. Among authors: kerr wg. Cytokine. 2023 Nov;171:156373. doi: 10.1016/j.cyto.2023.156373. Epub 2023 Sep 28. Cytokine. 2023. PMID: 37776719

5

Obesity control by SHIP inhibition requires pan-paralog inhibition and an intact eosinophil compartment.

Fernandes S, Srivastava N, Pedicone C, Sudan R, Luke EA, Dungan OM, Pacherille A, Meyer ST, Dormann S, Schurmans S, Chambers BJ, Chisholm JD, Kerr WG. Fernandes S, et al. Among authors: kerr wg. iScience. 2023 Jan 28;26(2):106071. doi: 10.1016/j.isci.2023.106071. eCollection 2023 Feb 17. iScience. 2023. PMID: 36818285 Free PMC article.

6

N1-Benzyl Tryptamine Pan-SHIP1/2 Inhibitors: Synthesis and Preliminary Biological Evaluation as Anti-Tumor Agents.

Fernandes S, Meyer ST, Shah JP, Adhikari AA, Kerr WG, Chisholm JD. Fernandes S, et al. Among authors: kerr wg. Molecules. 2022 Dec 2;27(23):8451. doi: 10.3390/molecules27238451. Molecules. 2022. PMID: 36500543 Free PMC article.

7

LRBA Deficiency Can Lead to Lethal Colitis That Is Diminished by SHIP1 Agonism.

Sudan R, Fernandes S, Srivastava N, Pedicone C, Meyer ST, Chisholm JD, Engelman RW, Kerr WG. Sudan R, et al. Among authors: kerr wg. Front Immunol. 2022 May 4;13:830961. doi: 10.3389/fimmu.2022.830961. eCollection 2022. Front Immunol. 2022. PMID: 35603158 Free PMC article.

8

Synthetic studies on the indane SHIP1 agonist AQX-1125.

Dungan OM, Dormann S, Fernandes S, Duffy BC, Effiong DG, Kerr WG, Chisholm JD. Dungan OM, et al. Among authors: kerr wg. Org Biomol Chem. 2022 May 18;20(19):4016-4020. doi: 10.1039/d2ob00555g. Org Biomol Chem. 2022. PMID: 35506893 Free PMC article.

9

Discovery of a novel SHIP1 agonist that promotes degradation of lipid-laden phagocytic cargo by microglia.

Pedicone C, Fernandes S, Matera A, Meyer ST, Loh S, Ha JH, Bernard D, Chisholm JD, Paolicelli RC, Kerr WG. Pedicone C, et al. Among authors: kerr wg. iScience. 2022 Mar 26;25(4):104170. doi: 10.1016/j.isci.2022.104170. eCollection 2022 Apr 15. iScience. 2022. PMID: 35465359 Free PMC article.

10

Selective deletion of SHIP-1 in hematopoietic cells in mice leads to severe lung inflammation involving ILC2 cells.

Ye X, Zhang F, Zhou L, Wei Y, Zhang L, Wang L, Tang H, Chen Z, Kerr WG, Zheng T, Zhu Z. Ye X, et al. Among authors: kerr wg. Sci Rep. 2021 Apr 28;11(1):9220. doi: 10.1038/s41598-021-88677-8. Sci Rep. 2021. PMID: 33911168 Free PMC article.

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