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Benzimidazoisoquinolines: a new class of rapidly metabolized aryl hydrocarbon receptor (AhR) ligands that induce AhR-dependent Tregs and prevent murine graft-versus-host disease.
Punj S, Kopparapu P, Jang HS, Phillips JL, Pennington J, Rohlman D, O'Donnell E, Iversen PL, Kolluri SK, Kerkvliet NI. Punj S, et al. Among authors: kerkvliet ni. PLoS One. 2014 Feb 19;9(2):e88726. doi: 10.1371/journal.pone.0088726. eCollection 2014. PLoS One. 2014. PMID: 24586378 Free PMC article.
AhR activation increases IL-2 production by alloreactive CD4+ T cells initiating the differentiation of mucosal-homing Tim3+ Lag3+ Tr1 cells.
Ehrlich AK, Pennington JM, Tilton S, Wang X, Marshall NB, Rohlman D, Funatake C, Punj S, O'Donnell E, Yu Z, Kolluri SK, Kerkvliet NI. Ehrlich AK, et al. Among authors: kerkvliet ni. Eur J Immunol. 2017 Nov;47(11):1989-2001. doi: 10.1002/eji.201747121. Epub 2017 Sep 15. Eur J Immunol. 2017. PMID: 28833046 Free PMC article.
122 results