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ATMP-classified, scalable, autologous cell spray for the treatment of skin wounds and assessment of its effects on wound healing clinically and on a molecular level.
Nuutila K, Katayama S, Laitinen A, Siltanen A, Patrikoski M, Valtonen J, Kankainen M, Kerkelä E, Kaartinen T, Juteau S, Korhonen M, Vuola J, Kankuri E. Nuutila K, et al. Among authors: kerkela e. Burns. 2023 Aug;49(5):1144-1156. doi: 10.1016/j.burns.2022.09.006. Epub 2022 Sep 16. Burns. 2023. PMID: 36195485 Free article.
Human bone marrow mesenchymal stem/stromal cells produce efficient localization in the brain and enhanced angiogenesis after intra-arterial delivery in rats with cerebral ischemia, but this is not translated to behavioral recovery.
Mitkari B, Nitzsche F, Kerkelä E, Kuptsova K, Huttunen J, Nystedt J, Korhonen M, Jolkkonen J. Mitkari B, et al. Among authors: kerkela e. Behav Brain Res. 2014 Feb 1;259:50-9. doi: 10.1016/j.bbr.2013.10.030. Epub 2013 Oct 29. Behav Brain Res. 2014. PMID: 24177208
Mesenchymal Stromal Cells and Their Extracellular Vesicles Enhance the Anti-Inflammatory Phenotype of Regulatory Macrophages by Downregulating the Production of Interleukin (IL)-23 and IL-22.
Hyvärinen K, Holopainen M, Skirdenko V, Ruhanen H, Lehenkari P, Korhonen M, Käkelä R, Laitinen S, Kerkelä E. Hyvärinen K, et al. Among authors: kerkela e. Front Immunol. 2018 Apr 12;9:771. doi: 10.3389/fimmu.2018.00771. eCollection 2018. Front Immunol. 2018. PMID: 29706969 Free PMC article.
51 results