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Microbe-host interplay in atopic dermatitis and psoriasis.
Fyhrquist N, Muirhead G, Prast-Nielsen S, Jeanmougin M, Olah P, Skoog T, Jules-Clement G, Feld M, Barrientos-Somarribas M, Sinkko H, van den Bogaard EH, Zeeuwen PLJM, Rikken G, Schalkwijk J, Niehues H, Däubener W, Eller SK, Alexander H, Pennino D, Suomela S, Tessas I, Lybeck E, Baran AM, Darban H, Gangwar RS, Gerstel U, Jahn K, Karisola P, Yan L, Hansmann B, Katayama S, Meller S, Bylesjö M, Hupé P, Levi-Schaffer F, Greco D, Ranki A, Schröder JM, Barker J, Kere J, Tsoka S, Lauerma A, Soumelis V, Nestle FO, Homey B, Andersson B, Alenius H. Fyhrquist N, et al. Among authors: kere j. Nat Commun. 2019 Oct 16;10(1):4703. doi: 10.1038/s41467-019-12253-y. Nat Commun. 2019. PMID: 31619666 Free PMC article.
Coding haplotype analysis supports HCR as the putative susceptibility gene for psoriasis at the MHC PSORS1 locus.
Asumalahti K, Veal C, Laitinen T, Suomela S, Allen M, Elomaa O, Moser M, de Cid R, Ripatti S, Vorechovsky I, Marcusson JA, Nakagawa H, Lazaro C, Estivill X, Capon F, Novelli G, Saarialho-Kere U, Barker J, Trembath R, Kere J; Psoriasis Consortium. Asumalahti K, et al. Among authors: kere j. Hum Mol Genet. 2002 Mar 1;11(5):589-97. doi: 10.1093/hmg/11.5.589. Hum Mol Genet. 2002. PMID: 11875053
Genetic analysis of PSORS1 distinguishes guttate psoriasis and palmoplantar pustulosis.
Asumalahti K, Ameen M, Suomela S, Hagforsen E, Michaëlsson G, Evans J, Munro M, Veal C, Allen M, Leman J, David Burden A, Kirby B, Connolly M, Griffiths CE, Trembath RC, Kere J, Saarialho-Kere U, Barker JN. Asumalahti K, et al. Among authors: kere j. J Invest Dermatol. 2003 Apr;120(4):627-32. doi: 10.1046/j.1523-1747.2003.12094.x. J Invest Dermatol. 2003. PMID: 12648227 Free article.
Transgenic mouse models support HCR as an effector gene in the PSORS1 locus.
Elomaa O, Majuri I, Suomela S, Asumalahti K, Jiao H, Mirzaei Z, Rozell B, Dahlman-Wright K, Pispa J, Kere J, Saarialho-Kere U. Elomaa O, et al. Among authors: kere j. Hum Mol Genet. 2004 Aug 1;13(15):1551-61. doi: 10.1093/hmg/ddh178. Epub 2004 Jun 9. Hum Mol Genet. 2004. PMID: 15190014
Elevated expression and genetic association links the SOCS3 gene to atopic dermatitis.
Ekelund E, Saaf A, Tengvall-Linder M, Melen E, Link J, Barker J, Reynolds NJ, Meggitt SJ, Kere J, Wahlgren CF, Pershagen G, Wickman M, Nordenskjold M, Kockum I, Bradley M. Ekelund E, et al. Among authors: kere j. Am J Hum Genet. 2006 Jun;78(6):1060-5. doi: 10.1086/504272. Epub 2006 Apr 14. Am J Hum Genet. 2006. PMID: 16685656 Free PMC article.
The CCHCR1 (HCR) gene is relevant for skin steroidogenesis and downregulated in cultured psoriatic keratinocytes.
Tiala I, Suomela S, Huuhtanen J, Wakkinen J, Hölttä-Vuori M, Kainu K, Ranta S, Turpeinen U, Hämäläinen E, Jiao H, Karvonen SL, Ikonen E, Kere J, Saarialho-Kere U, Elomaa O. Tiala I, et al. Among authors: kere j. J Mol Med (Berl). 2007 Jun;85(6):589-601. doi: 10.1007/s00109-006-0155-0. Epub 2007 Jan 13. J Mol Med (Berl). 2007. PMID: 17221218
Clinical associations of the risk alleles of HLA-Cw6 and CCHCR1*WWCC in psoriasis.
Suomela S, Kainu K, Onkamo P, Tiala I, Himberg J, Koskinen L, Snellman E, Karvonen SL, Karvonen J, Uurasmaa T, Reunala T, Kivikäs K, Jansén CT, Holopainen P, Elomaa O, Kere J, Saarialho-Kere U. Suomela S, et al. Among authors: kere j. Acta Derm Venereol. 2007;87(2):127-34. doi: 10.2340/00015555-0184. Acta Derm Venereol. 2007. PMID: 17340018 Free article.
608 results