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The Lipid Metabolism as Target and Modulator of BOLD-100 Anticancer Activity: Crosstalk with Histone Acetylation.
Baier D, Mendrina T, Schoenhacker-Alte B, Pirker C, Mohr T, Rusz M, Regner B, Schaier M, Sgarioto N, Raynal NJ, Nowikovsky K, Schmidt WM, Heffeter P, Meier-Menches SM, Koellensperger G, Keppler BK, Berger W. Baier D, et al. Among authors: keppler bk. Adv Sci (Weinh). 2023 Nov;10(32):e2301939. doi: 10.1002/advs.202301939. Epub 2023 Sep 26. Adv Sci (Weinh). 2023. PMID: 37752764 Free PMC article.
A novel EGFR inhibitor acts as potent tool for hypoxia-activated prodrug systems and exerts strong synergistic activity with VEGFR inhibition in vitro and in vivo.
Caban M, Koblmueller B, Groza D, Schueffl HH, Terenzi A, Tolios A, Mohr T, Mathuber M, Kryeziu K, Jaunecker C, Pirker C, Keppler BK, Berger W, Kowol CR, Heffeter P. Caban M, et al. Among authors: keppler bk. Cancer Lett. 2023 Jul 1;565:216237. doi: 10.1016/j.canlet.2023.216237. Epub 2023 May 19. Cancer Lett. 2023. PMID: 37211067 Free article.
Human serum albumin as a copper source for anticancer thiosemicarbazones.
Schaier M, Falcone E, Prstek T, Vileno B, Hager S, Keppler BK, Heffeter P, Koellensperger G, Faller P, Kowol CR. Schaier M, et al. Among authors: keppler bk. Metallomics. 2023 Aug 1;15(8):mfad046. doi: 10.1093/mtomcs/mfad046. Metallomics. 2023. PMID: 37505477 Free PMC article.
Insertion of (Bioactive) Equatorial Ligands into Platinum(IV) Complexes.
Kastner A, Schueffl H, Yassemipour PA, Keppler BK, Heffeter P, Kowol CR. Kastner A, et al. Among authors: keppler bk. Angew Chem Int Ed Engl. 2023 Nov 13;62(46):e202311468. doi: 10.1002/anie.202311468. Epub 2023 Oct 13. Angew Chem Int Ed Engl. 2023. PMID: 37703130 Free PMC article.
Synthesis and Preclinical Evaluation of Radiolabeled [103Ru]BOLD-100.
Happl B, Brandt M, Balber T, Benčurová K, Talip Z, Voegele A, Heffeter P, Kandioller W, Van der Meulen NP, Mitterhauser M, Hacker M, Keppler BK, Mindt TL. Happl B, et al. Among authors: keppler bk. Pharmaceutics. 2023 Nov 15;15(11):2626. doi: 10.3390/pharmaceutics15112626. Pharmaceutics. 2023. PMID: 38004604 Free PMC article.
Toward the boosted loading of cisplatin drug into liposome nanocarriers.
Wróblewska AM, Łukawska E, Wakuła Z, Zajda J, Keppler BK, Timerbaev AR, Matczuk M. Wróblewska AM, et al. Among authors: keppler bk. Eur J Pharm Biopharm. 2024 May;198:114245. doi: 10.1016/j.ejpb.2024.114245. Epub 2024 Mar 6. Eur J Pharm Biopharm. 2024. PMID: 38458266
456 results