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Biological Evaluation of the Antibacterial Retinoid CD437 in Cutibacterium acnes Infection.
Antimicrob Agents Chemother. 2023 Apr 18;67(4):e0167922. doi: 10.1128/aac.01679-22. Epub 2023 Mar 21.
Antimicrob Agents Chemother. 2023.
PMID: 36943064
Free PMC article.
A new class of synthetic retinoid antibiotics effective against bacterial persisters.
Kim W, Zhu W, Hendricks GL, Van Tyne D, Steele AD, Keohane CE, Fricke N, Conery AL, Shen S, Pan W, Lee K, Rajamuthiah R, Fuchs BB, Vlahovska PM, Wuest WM, Gilmore MS, Gao H, Ausubel FM, Mylonakis E.
Kim W, et al. Among authors: keohane ce.
Nature. 2018 Apr 5;556(7699):103-107. doi: 10.1038/nature26157. Epub 2018 Mar 28.
Nature. 2018.
PMID: 29590091
Free PMC article.
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Transcriptomic Profiling Suggests That Promysalin Alters the Metabolic Flux, Motility, and Iron Regulation in Pseudomonas putida KT2440.
Giglio KM, Keohane CE, Stodghill PV, Steele AD, Fetzer C, Sieber SA, Filiatrault MJ, Wuest WM.
Giglio KM, et al. Among authors: keohane ce.
ACS Infect Dis. 2018 Aug 10;4(8):1179-1187. doi: 10.1021/acsinfecdis.8b00041. Epub 2018 Jun 5.
ACS Infect Dis. 2018.
PMID: 29801413
Free PMC article.
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Total synthesis and biological investigation of (-)-promysalin.
Steele AD, Knouse KW, Keohane CE, Wuest WM.
Steele AD, et al. Among authors: keohane ce.
J Am Chem Soc. 2015 Jun 17;137(23):7314-7. doi: 10.1021/jacs.5b04767. Epub 2015 Jun 5.
J Am Chem Soc. 2015.
PMID: 26024439
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Promysalin Elicits Species-Selective Inhibition of Pseudomonas aeruginosa by Targeting Succinate Dehydrogenase.
Keohane CE, Steele AD, Fetzer C, Khowsathit J, Van Tyne D, Moynié L, Gilmore MS, Karanicolas J, Sieber SA, Wuest WM.
Keohane CE, et al.
J Am Chem Soc. 2018 Feb 7;140(5):1774-1782. doi: 10.1021/jacs.7b11212. Epub 2018 Jan 24.
J Am Chem Soc. 2018.
PMID: 29300464
Free PMC article.
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Target-Based Design of Promysalin Analogues Identifies a New Putative Binding Cleft in Succinate Dehydrogenase.
Post SJ, Keohane CE, Rossiter LM, Kaplan AR, Khowsathit J, Matuska K, Karanicolas J, Wuest WM.
Post SJ, et al. Among authors: keohane ce.
ACS Infect Dis. 2020 Jun 12;6(6):1372-1377. doi: 10.1021/acsinfecdis.0c00024. Epub 2020 Apr 14.
ACS Infect Dis. 2020.
PMID: 32286041
Free PMC article.
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Diverted Total Synthesis of Promysalin Analogs Demonstrates That an Iron-Binding Motif Is Responsible for Its Narrow-Spectrum Antibacterial Activity.
Steele AD, Keohane CE, Knouse KW, Rossiter SE, Williams SJ, Wuest WM.
Steele AD, et al. Among authors: keohane ce.
J Am Chem Soc. 2016 May 11;138(18):5833-6. doi: 10.1021/jacs.6b03373. Epub 2016 Apr 28.
J Am Chem Soc. 2016.
PMID: 27096543
Free PMC article.
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Correction to "Target-Based Design of Promysalin Analogs Identifies a New Putative Binding Cleft in Succinate Dehydrogenase".
Post SJ, Keohane CE, Rossiter LM, Kaplan AR, Khowsathit J, Matuska K, Karanicolas J, Wuest WM.
Post SJ, et al. Among authors: keohane ce.
ACS Infect Dis. 2022 Jul 8;8(7):1376. doi: 10.1021/acsinfecdis.2c00256. Epub 2022 Jun 6.
ACS Infect Dis. 2022.
PMID: 35801300
No abstract available.
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