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High Cysteinyl Leukotriene Receptor 1 Expression Correlates with Poor Survival of Uveal Melanoma Patients and Cognate Antagonist Drugs Modulate the Growth, Cancer Secretome, and Metabolism of Uveal Melanoma Cells.
Slater K, Heeran AB, Garcia-Mulero S, Kalirai H, Sanz-Pamplona R, Rahman A, Al-Attar N, Helmi M, O'Connell F, Bosch R, Portela A, Villanueva A, Gallagher WM, Jensen LD, Piulats JM, Coupland SE, O'Sullivan J, Kennedy BN. Slater K, et al. Among authors: kennedy bn. Cancers (Basel). 2020 Oct 13;12(10):2950. doi: 10.3390/cancers12102950. Cancers (Basel). 2020. PMID: 33066024 Free PMC article.
Increased topoisomerase IIalpha expression in colorectal cancer is associated with advanced disease and chemotherapeutic resistance via inhibition of apoptosis.
Coss A, Tosetto M, Fox EJ, Sapetto-Rebow B, Gorman S, Kennedy BN, Lloyd AT, Hyland JM, O'Donoghue DP, Sheahan K, Leahy DT, Mulcahy HE, O'Sullivan JN. Coss A, et al. Among authors: kennedy bn. Cancer Lett. 2009 Apr 18;276(2):228-38. doi: 10.1016/j.canlet.2008.11.018. Epub 2008 Dec 25. Cancer Lett. 2009. PMID: 19111388
Selective inhibition of retinal angiogenesis by targeting PI3 kinase.
Alvarez Y, Astudillo O, Jensen L, Reynolds AL, Waghorne N, Brazil DP, Cao Y, O'Connor JJ, Kennedy BN. Alvarez Y, et al. Among authors: kennedy bn. PLoS One. 2009 Nov 17;4(11):e7867. doi: 10.1371/journal.pone.0007867. PLoS One. 2009. PMID: 19924235 Free PMC article.
A Quininib Analogue and Cysteinyl Leukotriene Receptor Antagonist Inhibits Vascular Endothelial Growth Factor (VEGF)-independent Angiogenesis and Exerts an Additive Antiangiogenic Response with Bevacizumab.
Butler CT, Reynolds AL, Tosetto M, Dillon ET, Guiry PJ, Cagney G, O'Sullivan J, Kennedy BN. Butler CT, et al. Among authors: kennedy bn. J Biol Chem. 2017 Mar 3;292(9):3552-3567. doi: 10.1074/jbc.M116.747766. Epub 2016 Dec 29. J Biol Chem. 2017. PMID: 28035003 Free PMC article.
82 results