Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

87 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Characterization of the various functional pathways elicited by synthetic agonists or antagonists at the melatonin MT1 and MT2 receptors.
Legros C, Dupré C, Brasseur C, Bonnaud A, Bruno O, Valour D, Shabajee P, Giganti A, Nosjean O, Kenakin TP, Boutin JA. Legros C, et al. Among authors: kenakin tp. Pharmacol Res Perspect. 2019 Dec 29;8(1):e00539. doi: 10.1002/prp2.539. eCollection 2020 Feb. Pharmacol Res Perspect. 2019. PMID: 31893123 Free PMC article.
Enantiospecific Allosteric Modulation of Cannabinoid 1 Receptor.
Laprairie RB, Kulkarni PM, Deschamps JR, Kelly MEM, Janero DR, Cascio MG, Stevenson LA, Pertwee RG, Kenakin TP, Denovan-Wright EM, Thakur GA. Laprairie RB, et al. Among authors: kenakin tp. ACS Chem Neurosci. 2017 Jun 21;8(6):1188-1203. doi: 10.1021/acschemneuro.6b00310. Epub 2017 Feb 7. ACS Chem Neurosci. 2017. PMID: 28103441
Discovery of the Potent and Selective M1 PAM-Agonist N-[(3R,4S)-3-Hydroxytetrahydro-2H-pyran-4-yl]-5-methyl-4-[4-(1,3-thiazol-4-yl)benzyl]pyridine-2-carboxamide (PF-06767832): Evaluation of Efficacy and Cholinergic Side Effects.
Davoren JE, Lee CW, Garnsey M, Brodney MA, Cordes J, Dlugolenski K, Edgerton JR, Harris AR, Helal CJ, Jenkinson S, Kauffman GW, Kenakin TP, Lazzaro JT, Lotarski SM, Mao Y, Nason DM, Northcott C, Nottebaum L, O'Neil SV, Pettersen B, Popiolek M, Reinhart V, Salomon-Ferrer R, Steyn SJ, Webb D, Zhang L, Grimwood S. Davoren JE, et al. Among authors: kenakin tp. J Med Chem. 2016 Jul 14;59(13):6313-28. doi: 10.1021/acs.jmedchem.6b00544. Epub 2016 Jul 1. J Med Chem. 2016. PMID: 27275946
Novel 4,4-disubstituted piperidine-based C-C chemokine receptor-5 inhibitors with high potency against human immunodeficiency virus-1 and an improved human ether-a-go-go related gene (hERG) profile.
Kazmierski WM, Anderson DL, Aquino C, Chauder BA, Duan M, Ferris R, Kenakin T, Koble CS, Lang DG, McIntyre MS, Peckham J, Watson C, Wheelan P, Spaltenstein A, Wire MB, Svolto A, Youngman M. Kazmierski WM, et al. J Med Chem. 2011 Jun 9;54(11):3756-67. doi: 10.1021/jm200279v. Epub 2011 May 17. J Med Chem. 2011. PMID: 21539377
Development of 3-(4-Chlorophenyl)-1-(phenethyl)urea Analogues as Allosteric Modulators of the Cannabinoid Type-1 Receptor: RTICBM-189 is Brain Penetrant and Attenuates Reinstatement of Cocaine-Seeking Behavior.
Nguyen T, Gamage TF, Finlay DB, Decker AM, Langston TL, Barrus D, Glass M, Li JX, Kenakin TP, Zhang Y. Nguyen T, et al. Among authors: kenakin tp. J Med Chem. 2022 Jan 13;65(1):257-270. doi: 10.1021/acs.jmedchem.1c01432. Epub 2021 Dec 20. J Med Chem. 2022. PMID: 34929081 Free PMC article.
Interdependent allosteric free fatty acid receptor 2 modulators synergistically induce functional selective activation and desensitization in neutrophils.
Lind S, Holdfeldt A, Mårtensson J, Sundqvist M, Kenakin TP, Björkman L, Forsman H, Dahlgren C. Lind S, et al. Among authors: kenakin tp. Biochim Biophys Acta Mol Cell Res. 2020 Jun;1867(6):118689. doi: 10.1016/j.bbamcr.2020.118689. Epub 2020 Feb 21. Biochim Biophys Acta Mol Cell Res. 2020. PMID: 32092308 Free article.
87 results