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A decade of experience with genetically tailored pig models for diabetes and metabolic research.
Zettler S, Renner S, Kemter E, Hinrichs A, Klymiuk N, Backman M, Riedel EO, Mueller C, Streckel E, Braun-Reichhart C, Martins AS, Kurome M, Keßler B, Zakhartchenko V, Flenkenthaler F, Arnold GJ, Fröhlich T, Blum H, Blutke A, Wanke R, Wolf E. Zettler S, et al. Among authors: kemter e. Anim Reprod. 2020 Aug 26;17(3):e20200064. doi: 10.1590/1984-3143-AR2020-0064. Anim Reprod. 2020. PMID: 33029223 Free PMC article. Review.
Phenotypic and pathomorphological characteristics of a novel mutant mouse model for maturity-onset diabetes of the young type 2 (MODY 2).
van Bürck L, Blutke A, Kautz S, Rathkolb B, Klaften M, Wagner S, Kemter E, Hrabé de Angelis M, Wolf E, Aigner B, Wanke R, Herbach N. van Bürck L, et al. Among authors: kemter e. Am J Physiol Endocrinol Metab. 2010 Mar;298(3):E512-23. doi: 10.1152/ajpendo.00465.2009. Epub 2009 Dec 1. Am J Physiol Endocrinol Metab. 2010. PMID: 19952346 Free article.
Dystrophin-deficient pigs provide new insights into the hierarchy of physiological derangements of dystrophic muscle.
Klymiuk N, Blutke A, Graf A, Krause S, Burkhardt K, Wuensch A, Krebs S, Kessler B, Zakhartchenko V, Kurome M, Kemter E, Nagashima H, Schoser B, Herbach N, Blum H, Wanke R, Aartsma-Rus A, Thirion C, Lochmüller H, Walter MC, Wolf E. Klymiuk N, et al. Among authors: kemter e. Hum Mol Genet. 2013 Nov 1;22(21):4368-82. doi: 10.1093/hmg/ddt287. Epub 2013 Jun 19. Hum Mol Genet. 2013. PMID: 23784375
Regulatory sequences of the porcine THBD gene facilitate endothelial-specific expression of bioactive human thrombomodulin in single- and multitransgenic pigs.
Wuensch A, Baehr A, Bongoni AK, Kemter E, Blutke A, Baars W, Haertle S, Zakhartchenko V, Kurome M, Kessler B, Faber C, Abicht JM, Reichart B, Wanke R, Schwinzer R, Nagashima H, Rieben R, Ayares D, Wolf E, Klymiuk N. Wuensch A, et al. Among authors: kemter e. Transplantation. 2014 Jan 27;97(2):138-47. doi: 10.1097/TP.0b013e3182a95cbc. Transplantation. 2014. PMID: 24150517 Free article.
Uromodulin retention in thick ascending limb of Henle's loop affects SCD1 in neighboring proximal tubule: renal transcriptome studies in mouse models of uromodulin-associated kidney disease.
Horsch M, Beckers J, Fuchs H, Gailus-Durner V, Hrabě de Angelis M, Rathkolb B, Wolf E, Aigner B, Kemter E. Horsch M, et al. Among authors: kemter e. PLoS One. 2014 Nov 19;9(11):e113125. doi: 10.1371/journal.pone.0113125. eCollection 2014. PLoS One. 2014. PMID: 25409434 Free PMC article.
Pigs pave a way to de novo formation of functional human kidneys.
Kemter E, Wolf E. Kemter E, et al. Proc Natl Acad Sci U S A. 2015 Oct 20;112(42):12905-6. doi: 10.1073/pnas.1517582112. Epub 2015 Oct 12. Proc Natl Acad Sci U S A. 2015. PMID: 26460047 Free PMC article. No abstract available.
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