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Mitochondrial C5aR1 activity in macrophages controls IL-1β production underlying sterile inflammation.
Niyonzima N, Rahman J, Kunz N, West EE, Freiwald T, Desai JV, Merle NS, Gidon A, Sporsheim B, Lionakis MS, Evensen K, Lindberg B, Skagen K, Skjelland M, Singh P, Haug M, Ruseva MM, Kolev M, Bibby J, Marshall O, O'Brien B, Deeks N, Afzali B, Clark RJ, Woodruff TM, Pryor M, Yang ZH, Remaley AT, Mollnes TE, Hewitt SM, Yan B, Kazemian M, Kiss MG, Binder CJ, Halvorsen B, Espevik T, Kemper C. Niyonzima N, et al. Among authors: kemper c. Sci Immunol. 2021 Dec 24;6(66):eabf2489. doi: 10.1126/sciimmunol.abf2489. Epub 2021 Dec 24. Sci Immunol. 2021. PMID: 34932384 Free PMC article.
Intracellular complement activation sustains T cell homeostasis and mediates effector differentiation.
Liszewski MK, Kolev M, Le Friec G, Leung M, Bertram PG, Fara AF, Subias M, Pickering MC, Drouet C, Meri S, Arstila TP, Pekkarinen PT, Ma M, Cope A, Reinheckel T, Rodriguez de Cordoba S, Afzali B, Atkinson JP, Kemper C. Liszewski MK, et al. Among authors: kemper c. Immunity. 2013 Dec 12;39(6):1143-57. doi: 10.1016/j.immuni.2013.10.018. Epub 2013 Dec 5. Immunity. 2013. PMID: 24315997 Free PMC article.
Complement--tapping into new sites and effector systems.
Kolev M, Le Friec G, Kemper C. Kolev M, et al. Among authors: kemper c. Nat Rev Immunol. 2014 Dec;14(12):811-20. doi: 10.1038/nri3761. Epub 2014 Nov 14. Nat Rev Immunol. 2014. PMID: 25394942 Review.
Complement Regulates Nutrient Influx and Metabolic Reprogramming during Th1 Cell Responses.
Kolev M, Dimeloe S, Le Friec G, Navarini A, Arbore G, Povoleri GA, Fischer M, Belle R, Loeliger J, Develioglu L, Bantug GR, Watson J, Couzi L, Afzali B, Lavender P, Hess C, Kemper C. Kolev M, et al. Among authors: kemper c. Immunity. 2015 Jun 16;42(6):1033-47. doi: 10.1016/j.immuni.2015.05.024. Immunity. 2015. PMID: 26084023 Free PMC article.
T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4⁺ T cells.
Arbore G, West EE, Spolski R, Robertson AAB, Klos A, Rheinheimer C, Dutow P, Woodruff TM, Yu ZX, O'Neill LA, Coll RC, Sher A, Leonard WJ, Köhl J, Monk P, Cooper MA, Arno M, Afzali B, Lachmann HJ, Cope AP, Mayer-Barber KD, Kemper C. Arbore G, et al. Among authors: kemper c. Science. 2016 Jun 17;352(6292):aad1210. doi: 10.1126/science.aad1210. Science. 2016. PMID: 27313051 Free PMC article.
Keeping It All Going-Complement Meets Metabolism.
Kolev M, Kemper C. Kolev M, et al. Among authors: kemper c. Front Immunol. 2017 Jan 18;8:1. doi: 10.3389/fimmu.2017.00001. eCollection 2017. Front Immunol. 2017. PMID: 28149297 Free PMC article. Review.
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