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Choreography of AMPK activation.
Langendorf CG, Kemp BE. Langendorf CG, et al. Among authors: kemp be. Cell Res. 2015 Jan;25(1):5-6. doi: 10.1038/cr.2014.163. Epub 2014 Dec 5. Cell Res. 2015. PMID: 25475061 Free PMC article.
ATP sensitive bi-quinoline activator of the AMP-activated protein kinase.
Scott JW, Oakhill JS, Ling NX, Langendorf CG, Foitzik RC, Kemp BE, Issinger OG. Scott JW, et al. Among authors: kemp be. Biochem Biophys Res Commun. 2014 Jan 10;443(2):435-40. doi: 10.1016/j.bbrc.2013.11.130. Epub 2013 Dec 8. Biochem Biophys Res Commun. 2014. PMID: 24332941
Fake Inhibitors: AMPK Activation Trumps Inhibition.
Langendorf CG, Scott JW, Kemp BE. Langendorf CG, et al. Among authors: kemp be. Cell Chem Biol. 2017 Jul 20;24(7):775-777. doi: 10.1016/j.chembiol.2017.07.005. Cell Chem Biol. 2017. PMID: 28732195 Free article.
The autophagy initiator ULK1 sensitizes AMPK to allosteric drugs.
Dite TA, Ling NXY, Scott JW, Hoque A, Galic S, Parker BL, Ngoei KRW, Langendorf CG, O'Brien MT, Kundu M, Viollet B, Steinberg GR, Sakamoto K, Kemp BE, Oakhill JS. Dite TA, et al. Among authors: kemp be. Nat Commun. 2017 Sep 18;8(1):571. doi: 10.1038/s41467-017-00628-y. Nat Commun. 2017. PMID: 28924239 Free PMC article.
Long-chain fatty acyl-CoA esters regulate metabolism via allosteric control of AMPK β1 isoforms.
Pinkosky SL, Scott JW, Desjardins EM, Smith BK, Day EA, Ford RJ, Langendorf CG, Ling NXY, Nero TL, Loh K, Galic S, Hoque A, Smiles WJ, Ngoei KRW, Parker MW, Yan Y, Melcher K, Kemp BE, Oakhill JS, Steinberg GR. Pinkosky SL, et al. Among authors: kemp be. Nat Metab. 2020 Sep;2(9):873-881. doi: 10.1038/s42255-020-0245-2. Epub 2020 Jul 27. Nat Metab. 2020. PMID: 32719536 Free PMC article.
Structural Determinants for Small-Molecule Activation of Skeletal Muscle AMPK α2β2γ1 by the Glucose Importagog SC4.
Ngoei KRW, Langendorf CG, Ling NXY, Hoque A, Varghese S, Camerino MA, Walker SR, Bozikis YE, Dite TA, Ovens AJ, Smiles WJ, Jacobs R, Huang H, Parker MW, Scott JW, Rider MH, Foitzik RC, Kemp BE, Baell JB, Oakhill JS. Ngoei KRW, et al. Among authors: kemp be. Cell Chem Biol. 2018 Jun 21;25(6):728-737.e9. doi: 10.1016/j.chembiol.2018.03.008. Epub 2018 Apr 12. Cell Chem Biol. 2018. PMID: 29657085 Free article.
419 results