Kelly VP - Search Results

1

Knockout of ABCC1 in NCI-H441 cells reveals CF to be a suboptimal substrate to study MRP1 activity in organotypic in vitro models.

Sake JA, Selo MA, Burtnyak L, Dähnhardt HE, Helbet C, Mairinger S, Langer O, Kelly VP, Ehrhardt C. Sake JA, et al. Among authors: kelly vp. Eur J Pharm Sci. 2023 Feb 1;181:106364. doi: 10.1016/j.ejps.2022.106364. Epub 2022 Dec 20. Eur J Pharm Sci. 2023. PMID: 36563915 Free article.

2

Queuine Analogues Incorporating the 7-Aminomethyl-7-deazaguanine Core: Structure-Activity Relationships in the Treatment of Experimental Autoimmune Encephalomyelitis.

Cotter M, Varghese S, Chevot F, Fergus C, Kelly VP, Connon SJ, Southern JM. Cotter M, et al. Among authors: kelly vp. ChemMedChem. 2023 Sep 1;18(17):e202300207. doi: 10.1002/cmdc.202300207. Epub 2023 Jul 21. ChemMedChem. 2023. PMID: 37350546

3

Disruption to tRNA Modification by Queuine Contributes to Inflammatory Bowel Disease.

Zhang J, Zhang Y, McGrenaghan CJ, Kelly VP, Xia Y, Sun J. Zhang J, et al. Among authors: kelly vp. Cell Mol Gastroenterol Hepatol. 2023;15(6):1371-1389. doi: 10.1016/j.jcmgh.2023.02.006. Epub 2023 Feb 18. Cell Mol Gastroenterol Hepatol. 2023. PMID: 36801450 Free PMC article.

4

Networking to Optimize Dmd exon 53 Skipping in the Brain of mdx52 Mouse Model.

Doisy M, Vacca O, Fergus C, Gileadi T, Verhaeg M, Saoudi A, Tensorer T, Garcia L, Kelly VP, Montanaro F, Morgan JE, van Putten M, Aartsma-Rus A, Vaillend C, Muntoni F, Goyenvalle A. Doisy M, et al. Among authors: kelly vp. Biomedicines. 2023 Dec 7;11(12):3243. doi: 10.3390/biomedicines11123243. Biomedicines. 2023. PMID: 38137463 Free PMC article.

5

Investigating the Impact of Delivery Routes for Exon Skipping Therapies in the CNS of DMD Mouse Models.

Saoudi A, Fergus C, Gileadi T, Montanaro F, Morgan JE, Kelly VP, Tensorer T, Garcia L, Vaillend C, Muntoni F, Goyenvalle A. Saoudi A, et al. Among authors: kelly vp. Cells. 2023 Mar 15;12(6):908. doi: 10.3390/cells12060908. Cells. 2023. PMID: 36980249 Free PMC article.

6

Structural basis of Qng1-mediated salvage of the micronutrient queuine from queuosine-5'-monophosphate as the biological substrate.

Hung SH, Elliott GI, Ramkumar TR, Burtnyak L, McGrenaghan CJ, Alkuzweny S, Quaiyum S, Iwata-Reuyl D, Pan X, Green BD, Kelly VP, de Crécy-Lagard V, Swairjo MA. Hung SH, et al. Among authors: kelly vp. Nucleic Acids Res. 2023 Jan 25;51(2):935-951. doi: 10.1093/nar/gkac1231. Nucleic Acids Res. 2023. PMID: 36610787 Free PMC article.

7

Design and synthesis of multifunctional microtubule targeting agents endowed with dual pro-apoptotic and anti-autophagic efficacy.

Campiani G, Khan T, Ulivieri C, Staiano L, Papulino C, Magnano S, Nathwani S, Ramunno A, Lucena-Agell D, Relitti N, Federico S, Pozzetti L, Carullo G, Casagni A, Brogi S, Vanni F, Galatello P, Ghanim M, McCabe N, Lamponi S, Valoti M, Ibrahim O, O'Sullivan J, Turkington R, Kelly VP, VanWemmel R, Díaz JF, Gemma S, Zisterer D, Altucci L, De Matteis A, Butini S, Benedetti R. Campiani G, et al. Among authors: kelly vp. Eur J Med Chem. 2022 May 5;235:114274. doi: 10.1016/j.ejmech.2022.114274. Epub 2022 Mar 20. Eur J Med Chem. 2022. PMID: 35344902

8

De-novo designed β-lysine derivatives can both augment and diminish the proliferation rates of E. coli through the action of Elongation Factor P.

McDonnell CM, Ghanim M, Mike Southern J, Kelly VP, Connon SJ. McDonnell CM, et al. Among authors: kelly vp. Bioorg Med Chem Lett. 2022 Mar 1;59:128545. doi: 10.1016/j.bmcl.2022.128545. Epub 2022 Jan 12. Bioorg Med Chem Lett. 2022. PMID: 35032607

9

CRISPR/Cas9-mediated SARM1 knockout and epitope-tagged mice reveal that SARM1 does not regulate nuclear transcription, but is expressed in macrophages.

Doran CG, Sugisawa R, Carty M, Roche F, Fergus C, Hokamp K, Kelly VP, Bowie AG. Doran CG, et al. Among authors: kelly vp. J Biol Chem. 2021 Dec;297(6):101417. doi: 10.1016/j.jbc.2021.101417. Epub 2021 Nov 16. J Biol Chem. 2021. PMID: 34793837 Free PMC article.

10

A non-toxic, reversibly released imaging probe for oral cancer that is derived from natural compounds.

Ghanim M, Relitti N, McManus G, Butini S, Cappelli A, Campiani G, Mok KH, Kelly VP. Ghanim M, et al. Among authors: kelly vp. Sci Rep. 2021 Jul 7;11(1):14069. doi: 10.1038/s41598-021-93408-0. Sci Rep. 2021. PMID: 34234213 Free PMC article.

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