Kelly M - Search Results

1

Dual targeting of hepatocyte DGAT2 and stellate cell FASN alleviates nonalcoholic steatohepatitis in mice.

Yenilmez B, Harney S, DiMarzio C, Kelly M, Min K, Echeverria D, Bramato BM, Jackson SO, Reddig K, Kim JK, Khvorova A, Czech MP. Yenilmez B, et al. Among authors: kelly m. bioRxiv [Preprint]. 2023 Jul 5:2023.07.05.547848. doi: 10.1101/2023.07.05.547848. bioRxiv. 2023. PMID: 37461560 Free PMC article. Preprint.

2

Protein Kinase Mitogen-activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) Promotes Obesity-induced Hyperinsulinemia.

Roth Flach RJ, Danai LV, DiStefano MT, Kelly M, Menendez LG, Jurczyk A, Sharma RB, Jung DY, Kim JH, Kim JK, Bortell R, Alonso LC, Czech MP. Roth Flach RJ, et al. Among authors: kelly m. J Biol Chem. 2016 Jul 29;291(31):16221-30. doi: 10.1074/jbc.M116.718932. Epub 2016 May 20. J Biol Chem. 2016. PMID: 27226575 Free PMC article.

3

Map4k4 impairs energy metabolism in endothelial cells and promotes insulin resistance in obesity.

Roth Flach RJ, DiStefano MT, Danai LV, Senol-Cosar O, Yawe JC, Kelly M, Garcia Menendez L, Czech MP. Roth Flach RJ, et al. Among authors: kelly m. Am J Physiol Endocrinol Metab. 2017 Sep 1;313(3):E303-E313. doi: 10.1152/ajpendo.00037.2017. Epub 2017 Jun 13. Am J Physiol Endocrinol Metab. 2017. PMID: 28611026 Free PMC article.

4

Neuronal modulation of brown adipose activity through perturbation of white adipocyte lipogenesis.

Guilherme A, Pedersen DJ, Henriques F, Bedard AH, Henchey E, Kelly M, Morgan DA, Rahmouni K, Czech MP. Guilherme A, et al. Among authors: kelly m. Mol Metab. 2018 Oct;16:116-125. doi: 10.1016/j.molmet.2018.06.014. Epub 2018 Jun 27. Mol Metab. 2018. PMID: 30005879 Free PMC article.

5

CRISPR-delivery particles targeting nuclear receptor-interacting protein 1 (Nrip1) in adipose cells to enhance energy expenditure.

Shen Y, Cohen JL, Nicoloro SM, Kelly M, Yenilmez B, Henriques F, Tsagkaraki E, Edwards YJK, Hu X, Friedline RH, Kim JK, Czech MP. Shen Y, et al. Among authors: kelly m. J Biol Chem. 2018 Nov 2;293(44):17291-17305. doi: 10.1074/jbc.RA118.004554. Epub 2018 Sep 6. J Biol Chem. 2018. PMID: 30190322 Free PMC article.

6

Coronary disease is not associated with robust alterations in inflammatory gene expression in human epicardial fat.

Fitzgibbons TP, Lee N, Tran KV, Nicoloro S, Kelly M, Tam SK, Czech MP. Fitzgibbons TP, et al. Among authors: kelly m. JCI Insight. 2019 Oct 17;4(20):e124859. doi: 10.1172/jci.insight.124859. JCI Insight. 2019. PMID: 31513547 Free PMC article.

7

Control of Adipocyte Thermogenesis and Lipogenesis through β3-Adrenergic and Thyroid Hormone Signal Integration.

Guilherme A, Yenilmez B, Bedard AH, Henriques F, Liu D, Lee A, Goldstein L, Kelly M, Nicoloro SM, Chen M, Weinstein L, Collins S, Czech MP. Guilherme A, et al. Among authors: kelly m. Cell Rep. 2020 May 5;31(5):107598. doi: 10.1016/j.celrep.2020.107598. Cell Rep. 2020. PMID: 32375048 Free PMC article.

8

Single-Cell RNA Profiling Reveals Adipocyte to Macrophage Signaling Sufficient to Enhance Thermogenesis.

Henriques F, Bedard AH, Guilherme A, Kelly M, Chi J, Zhang P, Lifshitz LM, Bellvé K, Rowland LA, Yenilmez B, Kumar S, Wang Y, Luban J, Weinstein LS, Lin JD, Cohen P, Czech MP. Henriques F, et al. Among authors: kelly m. Cell Rep. 2020 Aug 4;32(5):107998. doi: 10.1016/j.celrep.2020.107998. Cell Rep. 2020. PMID: 32755590 Free PMC article.

9

An RNAi therapeutic targeting hepatic DGAT2 in a genetically obese mouse model of nonalcoholic steatohepatitis.

Yenilmez B, Wetoska N, Kelly M, Echeverria D, Min K, Lifshitz L, Alterman JF, Hassler MR, Hildebrand S, DiMarzio C, McHugh N, Vangjeli L, Sousa J, Pan M, Han X, Brehm MA, Khvorova A, Czech MP. Yenilmez B, et al. Among authors: kelly m. Mol Ther. 2022 Mar 2;30(3):1329-1342. doi: 10.1016/j.ymthe.2021.11.007. Epub 2021 Nov 11. Mol Ther. 2022. PMID: 34774753 Free PMC article.

10

CRISPR-enhanced human adipocyte browning as cell therapy for metabolic disease.

Tsagkaraki E, Nicoloro SM, DeSouza T, Solivan-Rivera J, Desai A, Lifshitz LM, Shen Y, Kelly M, Guilherme A, Henriques F, Amrani N, Ibraheim R, Rodriguez TC, Luk K, Maitland S, Friedline RH, Tauer L, Hu X, Kim JK, Wolfe SA, Sontheimer EJ, Corvera S, Czech MP. Tsagkaraki E, et al. Among authors: kelly m. Nat Commun. 2021 Nov 26;12(1):6931. doi: 10.1038/s41467-021-27190-y. Nat Commun. 2021. PMID: 34836963 Free PMC article.

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