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Single-cell RNA sequencing uncovers the nuclear decoy lincRNA PIRAT as a regulator of systemic monocyte immunity during COVID-19.
Aznaourova M, Schmerer N, Janga H, Zhang Z, Pauck K, Bushe J, Volkers SM, Wendisch D, Georg P, Ntini E, Aillaud M, Gündisch M, Mack E, Skevaki C, Keller C, Bauer C, Bertrams W, Marsico A, Nist A, Stiewe T, Gruber AD, Ruppert C, Li Y, Garn H, Sander LE, Schmeck B, Schulte LN. Aznaourova M, et al. Among authors: keller c. Proc Natl Acad Sci U S A. 2022 Sep 6;119(36):e2120680119. doi: 10.1073/pnas.2120680119. Epub 2022 Aug 23. Proc Natl Acad Sci U S A. 2022. PMID: 35998224 Free PMC article.
The janus-kinase inhibitor ruxolitinib in SARS-CoV-2 induced acute respiratory distress syndrome (ARDS).
Neubauer A, Johow J, Mack E, Burchert A, Meyn D, Kadlubiec A, Torje I, Wulf H, Vogelmeier CF, Hoyer J, Skevaki C, Muellenbach RM, Keller C, Schade-Brittinger C, Rolfes C, Wiesmann T. Neubauer A, et al. Among authors: keller c. Leukemia. 2021 Oct;35(10):2917-2923. doi: 10.1038/s41375-021-01374-3. Epub 2021 Aug 12. Leukemia. 2021. PMID: 34385593 Free PMC article. Clinical Trial.
Publisher Correction: The janus-kinase inhibitor ruxolitinib in SARS-CoV-2 induced acute respiratory distress syndrome (ARDS).
Neubauer A, Johow J, Mack E, Burchert A, Meyn D, Kadlubiec A, Torje I, Wulf H, Vogelmeier CF, Hoyer J, Skevaki C, Muellenbach RM, Keller C, Schade-Brittinger C, Rolfes C, Wiesmann T. Neubauer A, et al. Among authors: keller c. Leukemia. 2021 Oct;35(10):3038. doi: 10.1038/s41375-021-01412-0. Leukemia. 2021. PMID: 34518646 Free PMC article. No abstract available.
Serum proteomics hint at an early T-cell response and modulation of SARS-CoV-2-related pathogenic pathways in COVID-19-ARDS treated with Ruxolitinib.
Völkel S, Tarawneh TS, Sacher L, Bhagwat AM, Karim I, Mack HID, Wiesmann T, Beutel B, Hoyer J, Keller C, Renz H, Burchert A, Neubauer A, Graumann J, Skevaki C, Mack EKM. Völkel S, et al. Among authors: keller c. Front Med (Lausanne). 2023 May 24;10:1176427. doi: 10.3389/fmed.2023.1176427. eCollection 2023. Front Med (Lausanne). 2023. PMID: 37293294 Free PMC article.
Induction of robust cellular and humoral immunity against SARS-CoV-2 after a third dose of BNT162b2 vaccine in previously unresponsive older adults.
Romero-Olmedo AJ, Schulz AR, Hochstätter S, Das Gupta D, Virta I, Hirseland H, Staudenraus D, Camara B, Münch C, Hefter V, Sapre S, Krähling V, Müller-Kräuter H, Widera M, Mei HE, Keller C, Lohoff M. Romero-Olmedo AJ, et al. Among authors: keller c. Nat Microbiol. 2022 Feb;7(2):195-199. doi: 10.1038/s41564-021-01046-z. Epub 2022 Jan 10. Nat Microbiol. 2022. PMID: 35013593
TMPRSS2, a novel host-directed drug target against SARS-CoV-2.
Keller C, Böttcher-Friebertshäuser E, Lohoff M. Keller C, et al. Signal Transduct Target Ther. 2022 Jul 23;7(1):251. doi: 10.1038/s41392-022-01084-x. Signal Transduct Target Ther. 2022. PMID: 35871159 Free PMC article. No abstract available.
A type I interferon regulatory network for human plasmacytoid dendritic cells based on heparin, membrane-bound and soluble BDCA-2.
Venegas-Solis F, Staliunaite L, Rudolph E, Münch CC, Yu P, Freibert SA, Maeda T, Zimmer CL, Möbs C, Keller C, Kaufmann A, Bauer S. Venegas-Solis F, et al. Among authors: keller c. Proc Natl Acad Sci U S A. 2024 Mar 19;121(12):e2312404121. doi: 10.1073/pnas.2312404121. Epub 2024 Mar 13. Proc Natl Acad Sci U S A. 2024. PMID: 38478694
Dynamics of humoral and T-cell immunity after three BNT162b2 vaccinations in adults older than 80 years.
Romero-Olmedo AJ, Schulz AR, Hochstätter S, Gupta DD, Hirseland H, Staudenraus D, Camara B, Volland K, Hefter V, Sapre S, Krähling V, Müller-Kräuter H, Chung HR, Mei HE, Keller C, Lohoff M. Romero-Olmedo AJ, et al. Among authors: keller c. Lancet Infect Dis. 2022 May;22(5):588-589. doi: 10.1016/S1473-3099(22)00219-5. Epub 2022 Apr 6. Lancet Infect Dis. 2022. PMID: 35397209 Free PMC article. No abstract available.
1,825 results