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Detrimental effects of adenosine signaling in sickle cell disease.
Zhang Y, Dai Y, Wen J, Zhang W, Grenz A, Sun H, Tao L, Lu G, Alexander DC, Milburn MV, Carter-Dawson L, Lewis DE, Zhang W, Eltzschig HK, Kellems RE, Blackburn MR, Juneja HS, Xia Y. Zhang Y, et al. Among authors: kellems re. Nat Med. 2011 Jan;17(1):79-86. doi: 10.1038/nm.2280. Epub 2010 Dec 19. Nat Med. 2011. PMID: 21170046 Free PMC article.
Sustained Elevated Adenosine via ADORA2B Promotes Chronic Pain through Neuro-immune Interaction.
Hu X, Adebiyi MG, Luo J, Sun K, Le TT, Zhang Y, Wu H, Zhao S, Karmouty-Quintana H, Liu H, Huang A, Wen YE, Zaika OL, Mamenko M, Pochynyuk OM, Kellems RE, Eltzschig HK, Blackburn MR, Walters ET, Huang D, Hu H, Xia Y. Hu X, et al. Among authors: kellems re. Cell Rep. 2016 Jun 28;16(1):106-119. doi: 10.1016/j.celrep.2016.05.080. Epub 2016 Jun 16. Cell Rep. 2016. PMID: 27320922 Free PMC article.
Structural and Functional Insight of Sphingosine 1-Phosphate-Mediated Pathogenic Metabolic Reprogramming in Sickle Cell Disease.
Sun K, D'Alessandro A, Ahmed MH, Zhang Y, Song A, Ko TP, Nemkov T, Reisz JA, Wu H, Adebiyi M, Peng Z, Gong J, Liu H, Huang A, Wen YE, Wen AQ, Berka V, Bogdanov MV, Abdulmalik O, Han L, Tsai AL, Idowu M, Juneja HS, Kellems RE, Dowhan W, Hansen KC, Safo MK, Xia Y. Sun K, et al. Among authors: kellems re. Sci Rep. 2017 Nov 10;7(1):15281. doi: 10.1038/s41598-017-13667-8. Sci Rep. 2017. PMID: 29127281 Free PMC article.
Is preeclampsia an autoimmune disease?
Xia Y, Kellems RE. Xia Y, et al. Among authors: kellems re. Clin Immunol. 2009 Oct;133(1):1-12. doi: 10.1016/j.clim.2009.05.004. Epub 2009 Jun 5. Clin Immunol. 2009. PMID: 19501024 Free PMC article. Review.
Excess LIGHT contributes to placental impairment, increased secretion of vasoactive factors, hypertension, and proteinuria in preeclampsia.
Wang W, Parchim NF, Iriyama T, Luo R, Zhao C, Liu C, Irani RA, Zhang W, Ning C, Zhang Y, Blackwell SC, Chen L, Tao L, Hicks MJ, Kellems RE, Xia Y. Wang W, et al. Among authors: kellems re. Hypertension. 2014 Mar;63(3):595-606. doi: 10.1161/HYPERTENSIONAHA.113.02458. Epub 2013 Dec 9. Hypertension. 2014. PMID: 24324043 Free PMC article.
Elevated sphingosine-1-phosphate promotes sickling and sickle cell disease progression.
Zhang Y, Berka V, Song A, Sun K, Wang W, Zhang W, Ning C, Li C, Zhang Q, Bogdanov M, Alexander DC, Milburn MV, Ahmed MH, Lin H, Idowu M, Zhang J, Kato GJ, Abdulmalik OY, Zhang W, Dowhan W, Kellems RE, Zhang P, Jin J, Safo M, Tsai AL, Juneja HS, Xia Y. Zhang Y, et al. Among authors: kellems re. J Clin Invest. 2014 Jun;124(6):2750-61. doi: 10.1172/JCI74604. Epub 2014 May 16. J Clin Invest. 2014. PMID: 24837436 Free PMC article.
167 results