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Functional changes of the gastric bypass microbiota reactivate thermogenic adipose tissue and systemic glucose control via intestinal FXR-TGR5 crosstalk in diet-induced obesity.
Münzker J, Haase N, Till A, Sucher R, Haange SB, Nemetschke L, Gnad T, Jäger E, Chen J, Riede SJ, Chakaroun R, Massier L, Kovacs P, Ost M, Rolle-Kampczyk U, Jehmlich N, Weiner J, Heiker JT, Klöting N, Seeger G, Morawski M, Keitel V, Pfeifer A, von Bergen M, Heeren J, Krügel U, Fenske WK. Münzker J, et al. Among authors: keitel v. Microbiome. 2022 Jun 24;10(1):96. doi: 10.1186/s40168-022-01264-5. Microbiome. 2022. PMID: 35739571 Free PMC article.
Perspective: TGR5 (Gpbar-1) in liver physiology and disease.
Keitel V, Häussinger D. Keitel V, et al. Clin Res Hepatol Gastroenterol. 2012 Oct;36(5):412-9. doi: 10.1016/j.clinre.2012.03.008. Epub 2012 Apr 18. Clin Res Hepatol Gastroenterol. 2012. PMID: 22521118 Review.
TGR5 in cholangiocytes.
Keitel V, Häussinger D. Keitel V, et al. Curr Opin Gastroenterol. 2013 May;29(3):299-304. doi: 10.1097/MOG.0b013e32835f3f14. Curr Opin Gastroenterol. 2013. PMID: 23429467 Review.
Role of TGR5 (GPBAR1) in Liver Disease.
Keitel V, Häussinger D. Keitel V, et al. Semin Liver Dis. 2018 Nov;38(4):333-339. doi: 10.1055/s-0038-1669940. Epub 2018 Oct 24. Semin Liver Dis. 2018. PMID: 30357770 Review.
Targeting FXR in Cholestasis.
Keitel V, Dröge C, Häussinger D. Keitel V, et al. Handb Exp Pharmacol. 2019;256:299-324. doi: 10.1007/164_2019_231. Handb Exp Pharmacol. 2019. PMID: 31201556 Review.
Endocrine and paracrine role of bile acids.
Keitel V, Kubitz R, Häussinger D. Keitel V, et al. World J Gastroenterol. 2008 Oct 7;14(37):5620-9. doi: 10.3748/wjg.14.5620. World J Gastroenterol. 2008. PMID: 18837077 Free PMC article. Review.
184 results