Keinan S - Search Results

1

Crystal Structure of Cleaved Serp-1, a Myxomavirus-Derived Immune Modulating Serpin: Structural Design of Serpin Reactive Center Loop Peptides with Improved Therapeutic Function.

Mahon BP, Ambadapadi S, Yaron JR, Lomelino CL, Pinard MA, Keinan S, Kurnikov I, Macaulay C, Zhang L, Reeves W, McFadden G, Tibbetts S, McKenna R, Lucas AR. Mahon BP, et al. Among authors: keinan s. Biochemistry. 2018 Feb 20;57(7):1096-1107. doi: 10.1021/acs.biochem.7b01171. Epub 2018 Feb 6. Biochemistry. 2018. PMID: 29227673

2

Deriving Immune-Modulating Peptides from Viral Serine Protease Inhibitors (Serpins).

Yaron JR, Zhang L, Burgin M, Schutz LN, Awo EA, Keinan S, McFadden G, Ambadapadi S, Guo Q, Chen H, Lucas AR. Yaron JR, et al. Among authors: keinan s. Methods Mol Biol. 2021;2225:107-123. doi: 10.1007/978-1-0716-1012-1_7. Methods Mol Biol. 2021. PMID: 33108660

3

Immune protection is dependent on the gut microbiome in a lethal mouse gammaherpesviral infection.

Yaron JR, Ambadapadi S, Zhang L, Chavan RN, Tibbetts SA, Keinan S, Varsani A, Maldonado J, Kraberger S, Tafoya AM, Bullard WL, Kilbourne J, Stern-Harbutte A, Krajmalnik-Brown R, Munk BH, Koppang EO, Lim ES, Lucas AR. Yaron JR, et al. Among authors: keinan s. Sci Rep. 2020 Feb 11;10(1):2371. doi: 10.1038/s41598-020-59269-9. Sci Rep. 2020. PMID: 32047224 Free PMC article.

4

Computational modeling and in-vitro/in-silico correlation of phospholipid-based prodrugs for targeted drug delivery in inflammatory bowel disease.

Dahan A, Markovic M, Keinan S, Kurnikov I, Aponick A, Zimmermann EM, Ben-Shabat S. Dahan A, et al. Among authors: keinan s. J Comput Aided Mol Des. 2017 Nov;31(11):1021-1028. doi: 10.1007/s10822-017-0079-5. Epub 2017 Nov 3. J Comput Aided Mol Des. 2017. PMID: 29101519

5

Phospholipid-Based Prodrugs for Drug Targeting in Inflammatory Bowel Disease: Computational Optimization and In-Vitro Correlation.

Dahan A, Ben-Shabat S, Cohen N, Keinan S, Kurnikov I, Aponick A, Zimmermann EM. Dahan A, et al. Among authors: keinan s. Curr Top Med Chem. 2016;16(23):2543-8. doi: 10.2174/1568026616666160414122913. Curr Top Med Chem. 2016. PMID: 27086789

6

Phospholipid-Based Prodrugs for Colon-Targeted Drug Delivery: Experimental Study and In-Silico Simulations.

Markovic M, Dahan A, Keinan S, Kurnikov I, Aponick A, Zimmermann EM, Ben-Shabat S. Markovic M, et al. Among authors: keinan s. Pharmaceutics. 2019 Apr 16;11(4):186. doi: 10.3390/pharmaceutics11040186. Pharmaceutics. 2019. PMID: 30995772 Free PMC article.

7

Computational design and experimental characterization of a novel β-common receptor inhibitory peptide.

Kilar CR, Sekharan S, Sautina L, Diao Y, Keinan S, Shen Y, Bungert J, Mohandas R, Segal MS. Kilar CR, et al. Among authors: keinan s. Peptides. 2018 Jun;104:1-6. doi: 10.1016/j.peptides.2018.04.001. Epub 2018 Apr 7. Peptides. 2018. PMID: 29635062 Free PMC article.

8

In Silico Prediction of Ligand Binding Energies in Multiple Therapeutic Targets and Diverse Ligand Sets-A Case Study on BACE1, TYK2, HSP90, and PERK Proteins.

Frush EH, Sekharan S, Keinan S. Frush EH, et al. Among authors: keinan s. J Phys Chem B. 2017 Aug 31;121(34):8142-8148. doi: 10.1021/acs.jpcb.7b07224. Epub 2017 Aug 17. J Phys Chem B. 2017. PMID: 28759991

9

Lipidic prodrug approach for improved oral drug delivery and therapy.

Markovic M, Ben-Shabat S, Keinan S, Aponick A, Zimmermann EM, Dahan A. Markovic M, et al. Among authors: keinan s. Med Res Rev. 2019 Mar;39(2):579-607. doi: 10.1002/med.21533. Epub 2018 Oct 15. Med Res Rev. 2019. PMID: 30320896 Review.

10

Prospects and Challenges of Phospholipid-Based Prodrugs.

Markovic M, Ben-Shabat S, Keinan S, Aponick A, Zimmermann EM, Dahan A. Markovic M, et al. Among authors: keinan s. Pharmaceutics. 2018 Nov 1;10(4):210. doi: 10.3390/pharmaceutics10040210. Pharmaceutics. 2018. PMID: 30388756 Free PMC article.

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