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Transglutaminase inhibitors: a patent review.
Keillor JW, Apperley KY. Keillor JW, et al. Expert Opin Ther Pat. 2016;26(1):49-63. doi: 10.1517/13543776.2016.1115836. Epub 2015 Nov 24. Expert Opin Ther Pat. 2016. PMID: 26560530 Review.
Irreversible inhibitors of tissue transglutaminase.
Keillor JW, Chabot N, Roy I, Mulani A, Leogane O, Pardin C. Keillor JW, et al. Adv Enzymol Relat Areas Mol Biol. 2011;78:415-47. doi: 10.1002/9781118105771.ch10. Adv Enzymol Relat Areas Mol Biol. 2011. PMID: 22220480 Review. No abstract available.
Acyl transfer mechanisms of tissue transglutaminase.
Keillor JW, Clouthier CM, Apperley KYP, Akbar A, Mulani A. Keillor JW, et al. Bioorg Chem. 2014 Dec;57:186-197. doi: 10.1016/j.bioorg.2014.06.003. Epub 2014 Jun 25. Bioorg Chem. 2014. PMID: 25035302 Review.
Inhibitors of tissue transglutaminase.
Keillor JW, Apperley KY, Akbar A. Keillor JW, et al. Trends Pharmacol Sci. 2015 Jan;36(1):32-40. doi: 10.1016/j.tips.2014.10.014. Epub 2014 Dec 12. Trends Pharmacol Sci. 2015. PMID: 25500711 Review.
Inhibition or ablation of transglutaminase 2 impairs astrocyte migration.
Monteagudo A, Ji C, Akbar A, Keillor JW, Johnson GVW. Monteagudo A, et al. Among authors: keillor jw. Biochem Biophys Res Commun. 2017 Jan 22;482(4):942-947. doi: 10.1016/j.bbrc.2016.11.137. Epub 2016 Nov 27. Biochem Biophys Res Commun. 2017. PMID: 27899316 Free PMC article.
Transamidase site-targeted agents alter the conformation of the transglutaminase cancer stem cell survival protein to reduce GTP binding activity and cancer stem cell survival.
Kerr C, Szmacinski H, Fisher ML, Nance B, Lakowicz JR, Akbar A, Keillor JW, Lok Wong T, Godoy-Ruiz R, Toth EA, Weber DJ, Eckert RL. Kerr C, et al. Among authors: keillor jw. Oncogene. 2017 May 25;36(21):2981-2990. doi: 10.1038/onc.2016.452. Epub 2016 Dec 12. Oncogene. 2017. PMID: 27941875 Free PMC article.
Hydroxy-substituted trans-cinnamoyl derivatives as multifunctional tools in the context of Alzheimer's disease.
De Simone A, Bartolini M, Baschieri A, Apperley KYP, Chen HH, Guardigni M, Montanari S, Kobrlova T, Soukup O, Valgimigli L, Andrisano V, Keillor JW, Basso M, Milelli A. De Simone A, et al. Among authors: keillor jw. Eur J Med Chem. 2017 Oct 20;139:378-389. doi: 10.1016/j.ejmech.2017.07.058. Epub 2017 Jul 25. Eur J Med Chem. 2017. PMID: 28810189
106 results