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RNA sequencing of long-term label-retaining colon cancer stem cells identifies novel regulators of quiescence.
Regan JL, Schumacher D, Staudte S, Steffen A, Lesche R, Toedling J, Jourdan T, Haybaeck J, Mumberg D, Henderson D, Győrffy B, Regenbrecht CRA, Keilholz U, Schäfer R, Lange M. Regan JL, et al. Among authors: keilholz u. iScience. 2021 May 24;24(6):102618. doi: 10.1016/j.isci.2021.102618. eCollection 2021 Jun 25. iScience. 2021. PMID: 34142064 Free PMC article.
Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors.
Schütte M, Risch T, Abdavi-Azar N, Boehnke K, Schumacher D, Keil M, Yildiriman R, Jandrasits C, Borodina T, Amstislavskiy V, Worth CL, Schweiger C, Liebs S, Lange M, Warnatz HJ, Butcher LM, Barrett JE, Sultan M, Wierling C, Golob-Schwarzl N, Lax S, Uranitsch S, Becker M, Welte Y, Regan JL, Silvestrov M, Kehler I, Fusi A, Kessler T, Herwig R, Landegren U, Wienke D, Nilsson M, Velasco JA, Garin-Chesa P, Reinhard C, Beck S, Schäfer R, Regenbrecht CR, Henderson D, Lange B, Haybaeck J, Keilholz U, Hoffmann J, Lehrach H, Yaspo ML. Schütte M, et al. Among authors: keilholz u. Nat Commun. 2017 Feb 10;8:14262. doi: 10.1038/ncomms14262. Nat Commun. 2017. PMID: 28186126 Free PMC article.
Non-Canonical Hedgehog Signaling Is a Positive Regulator of the WNT Pathway and Is Required for the Survival of Colon Cancer Stem Cells.
Regan JL, Schumacher D, Staudte S, Steffen A, Haybaeck J, Keilholz U, Schweiger C, Golob-Schwarzl N, Mumberg D, Henderson D, Lehrach H, Regenbrecht CRA, Schäfer R, Lange M. Regan JL, et al. Among authors: keilholz u. Cell Rep. 2017 Dec 5;21(10):2813-2828. doi: 10.1016/j.celrep.2017.11.025. Cell Rep. 2017. PMID: 29212028 Free article.
Heterogeneous pathway activation and drug response modelled in colorectal-tumor-derived 3D cultures.
Schumacher D, Andrieux G, Boehnke K, Keil M, Silvestri A, Silvestrov M, Keilholz U, Haybaeck J, Erdmann G, Sachse C, Templin M, Hoffmann J, Boerries M, Schäfer R, Regenbrecht CRA. Schumacher D, et al. Among authors: keilholz u. PLoS Genet. 2019 Mar 29;15(3):e1008076. doi: 10.1371/journal.pgen.1008076. eCollection 2019 Mar. PLoS Genet. 2019. PMID: 30925167 Free PMC article.
Multiplexed Quantification of Four Neuroblastoma DNA Targets in a Single Droplet Digital PCR Reaction.
Peitz C, Sprüssel A, Linke RB, Astrahantseff K, Grimaldi M, Schmelz K, Toedling J, Schulte JH, Fischer M, Messerschmidt C, Beule D, Keilholz U, Eggert A, Deubzer HE, Lodrini M. Peitz C, et al. Among authors: keilholz u. J Mol Diagn. 2020 Nov;22(11):1309-1323. doi: 10.1016/j.jmoldx.2020.07.006. Epub 2020 Aug 26. J Mol Diagn. 2020. PMID: 32858250 Free article.
Comparative Analysis of Public Knowledge Bases for Precision Oncology.
Pallarz S, Benary M, Lamping M, Rieke D, Starlinger J, Sers C, Wiegandt DL, Seibert M, Ševa J, Schäfer R, Keilholz U, Leser U. Pallarz S, et al. Among authors: keilholz u. JCO Precis Oncol. 2019 Jul 24;3:PO.18.00371. doi: 10.1200/PO.18.00371. eCollection 2019. JCO Precis Oncol. 2019. PMID: 32914021 Free PMC article.
415 results