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Control mechanisms in germ cells mediated by p53 family proteins.
Gebel J, Tuppi M, Krauskopf K, Coutandin D, Pitzius S, Kehrloesser S, Osterburg C, Dötsch V. Gebel J, et al. Among authors: kehrloesser s. J Cell Sci. 2017 Aug 9:jcs.204859. doi: 10.1242/jcs.204859. Online ahead of print. J Cell Sci. 2017. PMID: 28794013 Review.
Analysis of the oligomeric state and transactivation potential of TAp73α.
Luh LM, Kehrloesser S, Deutsch GB, Gebel J, Coutandin D, Schäfer B, Agostini M, Melino G, Dötsch V. Luh LM, et al. Among authors: kehrloesser s. Cell Death Differ. 2013 Aug;20(8):1008-16. doi: 10.1038/cdd.2013.23. Epub 2013 Mar 29. Cell Death Differ. 2013. PMID: 23538419 Free PMC article.
Functional interplay between MDM2, p63/p73 and mutant p53.
Stindt MH, Muller PA, Ludwig RL, Kehrloesser S, Dötsch V, Vousden KH. Stindt MH, et al. Among authors: kehrloesser s. Oncogene. 2015 Aug 13;34(33):4300-10. doi: 10.1038/onc.2014.359. Epub 2014 Nov 24. Oncogene. 2015. PMID: 25417702 Free PMC article.
Structural Evolution and Dynamics of the p53 Proteins.
Chillemi G, Kehrloesser S, Bernassola F, Desideri A, Dötsch V, Levine AJ, Melino G. Chillemi G, et al. Among authors: kehrloesser s. Cold Spring Harb Perspect Med. 2017 Apr 3;7(4):a028308. doi: 10.1101/cshperspect.a028308. Cold Spring Harb Perspect Med. 2017. PMID: 27091942 Free PMC article. Review.
Apoptosis inhibitor 5 is an endogenous inhibitor of caspase-2.
Imre G, Berthelet J, Heering J, Kehrloesser S, Melzer IM, Lee BI, Thiede B, Dötsch V, Rajalingam K. Imre G, et al. Among authors: kehrloesser s. EMBO Rep. 2017 May;18(5):733-744. doi: 10.15252/embr.201643744. Epub 2017 Mar 23. EMBO Rep. 2017. PMID: 28336776 Free PMC article.
Protein aggregation of the p63 transcription factor underlies severe skin fragility in AEC syndrome.
Russo C, Osterburg C, Sirico A, Antonini D, Ambrosio R, Würz JM, Rinnenthal J, Ferniani M, Kehrloesser S, Schäfer B, Güntert P, Sinha S, Dötsch V, Missero C. Russo C, et al. Among authors: kehrloesser s. Proc Natl Acad Sci U S A. 2018 Jan 30;115(5):E906-E915. doi: 10.1073/pnas.1713773115. Epub 2018 Jan 16. Proc Natl Acad Sci U S A. 2018. PMID: 29339502 Free PMC article.
Oocyte DNA damage quality control requires consecutive interplay of CHK2 and CK1 to activate p63.
Tuppi M, Kehrloesser S, Coutandin DW, Rossi V, Luh LM, Strubel A, Hötte K, Hoffmeister M, Schäfer B, De Oliveira T, Greten F, Stelzer EHK, Knapp S, De Felici M, Behrends C, Klinger FG, Dötsch V. Tuppi M, et al. Among authors: kehrloesser s. Nat Struct Mol Biol. 2018 Mar;25(3):261-269. doi: 10.1038/s41594-018-0035-7. Epub 2018 Feb 26. Nat Struct Mol Biol. 2018. PMID: 29483652
CHK2 sets the stage for CK1 in oocyte quality control.
Kehrloesser S, Tuppi M, Dötsch V. Kehrloesser S, et al. Cell Death Differ. 2018 Jun;25(6):1007-1009. doi: 10.1038/s41418-018-0107-6. Cell Death Differ. 2018. PMID: 29666471 Free PMC article. No abstract available.
16 results