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A novel ACE2 decoy for both neutralization of SARS-CoV-2 variants and killing of infected cells.
Kegler A, Drewitz L, Arndt C, Daglar C, Rodrigues Loureiro L, Mitwasi N, Neuber C, González Soto KE, Bartsch T, Baraban L, Ziehr H, Heine M, Nieter A, Moreira-Soto A, Kühne A, Drexler JF, Seliger B, Laube M, Máthé D, Pályi B, Hajdrik P, Forgách L, Kis Z, Szigeti K, Bergmann R, Feldmann A, Bachmann M. Kegler A, et al. Front Immunol. 2023 Jun 13;14:1204543. doi: 10.3389/fimmu.2023.1204543. eCollection 2023. Front Immunol. 2023. PMID: 37383226 Free PMC article.
Retargeting of T lymphocytes to PSCA- or PSMA positive prostate cancer cells using the novel modular chimeric antigen receptor platform technology "UniCAR".
Feldmann A, Arndt C, Bergmann R, Loff S, Cartellieri M, Bachmann D, Aliperta R, Hetzenecker M, Ludwig F, Albert S, Ziller-Walter P, Kegler A, Koristka S, Gärtner S, Schmitz M, Ehninger A, Ehninger G, Pietzsch J, Steinbach J, Bachmann M. Feldmann A, et al. Among authors: kegler a. Oncotarget. 2017 May 9;8(19):31368-31385. doi: 10.18632/oncotarget.15572. Oncotarget. 2017. PMID: 28404896 Free PMC article.
A novel nanobody-based target module for retargeting of T lymphocytes to EGFR-expressing cancer cells via the modular UniCAR platform.
Albert S, Arndt C, Feldmann A, Bergmann R, Bachmann D, Koristka S, Ludwig F, Ziller-Walter P, Kegler A, Gärtner S, Schmitz M, Ehninger A, Cartellieri M, Ehninger G, Pietzsch HJ, Pietzsch J, Steinbach J, Bachmann M. Albert S, et al. Among authors: kegler a. Oncoimmunology. 2017 Feb 6;6(4):e1287246. doi: 10.1080/2162402X.2017.1287246. eCollection 2017. Oncoimmunology. 2017. PMID: 28507794 Free PMC article.
Development of novel target modules for retargeting of UniCAR T cells to GD2 positive tumor cells.
Mitwasi N, Feldmann A, Bergmann R, Berndt N, Arndt C, Koristka S, Kegler A, Jureczek J, Hoffmann A, Ehninger A, Cartellieri M, Albert S, Rossig C, Ehninger G, Pietzsch J, Steinbach J, Bachmann M. Mitwasi N, et al. Among authors: kegler a. Oncotarget. 2017 Sep 18;8(65):108584-108603. doi: 10.18632/oncotarget.21017. eCollection 2017 Dec 12. Oncotarget. 2017. PMID: 29312553 Free PMC article.
Retargeting of UniCAR T cells with an in vivo synthesized target module directed against CD19 positive tumor cells.
Bachmann D, Aliperta R, Bergmann R, Feldmann A, Koristka S, Arndt C, Loff S, Welzel P, Albert S, Kegler A, Ehninger A, Cartellieri M, Ehninger G, Bornhäuser M, von Bonin M, Werner C, Pietzsch J, Steinbach J, Bachmann M. Bachmann D, et al. Among authors: kegler a. Oncotarget. 2017 Dec 21;9(7):7487-7500. doi: 10.18632/oncotarget.23556. eCollection 2018 Jan 26. Oncotarget. 2017. PMID: 29484126 Free PMC article.
Engrafting human regulatory T cells with a flexible modular chimeric antigen receptor technology.
Koristka S, Kegler A, Bergmann R, Arndt C, Feldmann A, Albert S, Cartellieri M, Ehninger A, Ehninger G, Middeke JM, Bornhäuser M, Schmitz M, Pietzsch J, Akgün K, Ziemssen T, Steinbach J, Bachmann MP. Koristka S, et al. Among authors: kegler a. J Autoimmun. 2018 Jun;90:116-131. doi: 10.1016/j.jaut.2018.02.006. Epub 2018 Mar 2. J Autoimmun. 2018. PMID: 29503042
Anti-CAR-engineered T cells for epitope-based elimination of autologous CAR T cells.
Koristka S, Ziller-Walter P, Bergmann R, Arndt C, Feldmann A, Kegler A, Cartellieri M, Ehninger A, Ehninger G, Bornhäuser M, Bachmann MP. Koristka S, et al. Among authors: kegler a. Cancer Immunol Immunother. 2019 Sep;68(9):1401-1415. doi: 10.1007/s00262-019-02376-y. Epub 2019 Aug 14. Cancer Immunol Immunother. 2019. PMID: 31414180 Free PMC article.
A theranostic PSMA ligand for PET imaging and retargeting of T cells expressing the universal chimeric antigen receptor UniCAR.
Arndt C, Feldmann A, Koristka S, Schäfer M, Bergmann R, Mitwasi N, Berndt N, Bachmann D, Kegler A, Schmitz M, Puentes-Cala E, Soto JA, Ehninger G, Pietzsch J, Liolios C, Wunderlich G, Kotzerke J, Kopka K, Bachmann M. Arndt C, et al. Among authors: kegler a. Oncoimmunology. 2019 Sep 7;8(11):1659095. doi: 10.1080/2162402X.2019.1659095. eCollection 2019. Oncoimmunology. 2019. PMID: 31646084 Free PMC article.
43 results