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Structural and functional basis of inositol hexaphosphate stimulation of NHEJ through stabilization of Ku-XLF interaction.
Kefala Stavridi A, Gontier A, Morin V, Frit P, Ropars V, Barboule N, Racca C, Jonchhe S, Morten MJ, Andreani J, Rak A, Legrand P, Bourand-Plantefol A, Hardwick SW, Chirgadze DY, Davey P, De Oliveira TM, Rothenberg E, Britton S, Calsou P, Blundell TL, Varela PF, Chaplin AK, Charbonnier JB. Kefala Stavridi A, et al. Nucleic Acids Res. 2023 Nov 27;51(21):11732-11747. doi: 10.1093/nar/gkad863. Nucleic Acids Res. 2023. PMID: 37870477 Free PMC article.
Pre-RNA splicing in metabolic homeostasis and liver disease.
Jobbins AM, Yu S, Paterson HAB, Maude H, Kefala-Stavridi A, Speck C, Cebola I, Vernia S. Jobbins AM, et al. Among authors: kefala stavridi a. Trends Endocrinol Metab. 2023 Dec;34(12):823-837. doi: 10.1016/j.tem.2023.08.007. Epub 2023 Sep 4. Trends Endocrinol Metab. 2023. PMID: 37673766 Free article. Review.
PAXX binding to the NHEJ machinery explains functional redundancy with XLF.
Seif-El-Dahan M, Kefala-Stavridi A, Frit P, Hardwick SW, Chirgadze DY, Maia De Oliviera T, Andreani J, Britton S, Barboule N, Bossaert M, Pandurangan AP, Meek K, Blundell TL, Ropars V, Calsou P, Charbonnier JB, Chaplin AK. Seif-El-Dahan M, et al. Among authors: kefala stavridi a. Sci Adv. 2023 Jun 2;9(22):eadg2834. doi: 10.1126/sciadv.adg2834. Epub 2023 May 31. Sci Adv. 2023. PMID: 37256950 Free PMC article.
Dimers of DNA-PK create a stage for DNA double-strand break repair.
Chaplin AK, Hardwick SW, Liang S, Kefala Stavridi A, Hnizda A, Cooper LR, De Oliveira TM, Chirgadze DY, Blundell TL. Chaplin AK, et al. Among authors: kefala stavridi a. Nat Struct Mol Biol. 2021 Jan;28(1):13-19. doi: 10.1038/s41594-020-00517-x. Epub 2020 Oct 19. Nat Struct Mol Biol. 2021. PMID: 33077952