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Covalent fragment libraries in drug discovery.
Keeley A, Petri L, Ábrányi-Balogh P, Keserű GM. Keeley A, et al. Drug Discov Today. 2020 Jun;25(6):983-996. doi: 10.1016/j.drudis.2020.03.016. Epub 2020 Apr 13. Drug Discov Today. 2020. PMID: 32298798 Free article. Review.
Heterocyclic electrophiles as new MurA inhibitors.
Keeley A, Ábrányi-Balogh P, Hrast M, Imre T, Ilaš J, Gobec S, Keserű GM. Keeley A, et al. Arch Pharm (Weinheim). 2018 Dec;351(12):e1800184. doi: 10.1002/ardp.201800184. Epub 2018 Nov 21. Arch Pharm (Weinheim). 2018. PMID: 30461051
Crystallographic and electrophilic fragment screening of the SARS-CoV-2 main protease.
Douangamath A, Fearon D, Gehrtz P, Krojer T, Lukacik P, Owen CD, Resnick E, Strain-Damerell C, Aimon A, Ábrányi-Balogh P, Brandão-Neto J, Carbery A, Davison G, Dias A, Downes TD, Dunnett L, Fairhead M, Firth JD, Jones SP, Keeley A, Keserü GM, Klein HF, Martin MP, Noble MEM, O'Brien P, Powell A, Reddi RN, Skyner R, Snee M, Waring MJ, Wild C, London N, von Delft F, Walsh MA. Douangamath A, et al. Among authors: keeley a. Nat Commun. 2020 Oct 7;11(1):5047. doi: 10.1038/s41467-020-18709-w. Nat Commun. 2020. PMID: 33028810 Free PMC article.
Next-Generation Heterocyclic Electrophiles as Small-Molecule Covalent MurA Inhibitors.
Ábrányi-Balogh P, Keeley A, Ferenczy GG, Petri L, Imre T, Grabrijan K, Hrast M, Knez D, Ilaš J, Gobec S, Keserű GM. Ábrányi-Balogh P, et al. Among authors: keeley a. Pharmaceuticals (Basel). 2022 Nov 29;15(12):1484. doi: 10.3390/ph15121484. Pharmaceuticals (Basel). 2022. PMID: 36558935 Free PMC article.
Activation-Free Sulfonyl Fluoride Probes for Fragment Screening.
Petri L, Ábrányi-Balogh P, Csorba N, Keeley A, Simon J, Ranđelović I, Tóvári J, Schlosser G, Szabó D, Drahos L, Keserű GM. Petri L, et al. Among authors: keeley a. Molecules. 2023 Mar 29;28(7):3042. doi: 10.3390/molecules28073042. Molecules. 2023. PMID: 37049805 Free PMC article.
Streptococcus pyogenes carriage and infection within households in The Gambia: a longitudinal cohort study.
Armitage EP, de Crombrugghe G, Keeley AJ, Senghore E, Camara FE, Jammeh M, Bittaye A, Ceesay H, Ceesay I, Samateh B, Manneh M, Kampmann B, Turner CE, Kucharski A, Botteaux A, Smeesters PR, de Silva TI, Marks M; MRCG StrepA Study Group. Armitage EP, et al. Among authors: keeley aj. Lancet Microbe. 2024 May 2:S2666-5247(24)00046-6. doi: 10.1016/S2666-5247(24)00046-6. Online ahead of print. Lancet Microbe. 2024. PMID: 38735305 Free article.
Ecological countermeasures to prevent pathogen spillover and subsequent pandemics.
Plowright RK, Ahmed AN, Coulson T, Crowther TW, Ejotre I, Faust CL, Frick WF, Hudson PJ, Kingston T, Nameer PO, O'Mara MT, Peel AJ, Possingham H, Razgour O, Reeder DM, Ruiz-Aravena M, Simmons NB, Srinivas PN, Tabor GM, Tanshi I, Thompson IG, Vanak AT, Vora NM, Willison CE, Keeley ATH. Plowright RK, et al. Among authors: keeley ath. Nat Commun. 2024 Mar 26;15(1):2577. doi: 10.1038/s41467-024-46151-9. Nat Commun. 2024. PMID: 38531842 Free PMC article. Review.
Health-seeking behaviour and beliefs around sore throat in The Gambia: A qualitative study.
Suau Sans M, Manneh M, Ceesay I, Bittaye A, de Crombrugghe G, Keeley AJ, de Silva TI, Palmer J, Armitage EP, Marks M; MRCG Strep A Study Group. Suau Sans M, et al. Among authors: keeley aj. PLOS Glob Public Health. 2024 Mar 25;4(3):e0002257. doi: 10.1371/journal.pgph.0002257. eCollection 2024. PLOS Glob Public Health. 2024. PMID: 38527043 Free PMC article.
131 results