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Rhinovirus-induced epithelial RIG-I inflammasome suppresses antiviral immunity and promotes inflammation in asthma and COVID-19.
Radzikowska U, Eljaszewicz A, Tan G, Stocker N, Heider A, Westermann P, Steiner S, Dreher A, Wawrzyniak P, Rückert B, Rodriguez-Coira J, Zhakparov D, Huang M, Jakiela B, Sanak M, Moniuszko M, O'Mahony L, Jutel M, Kebadze T, Jackson DJ, Edwards MR, Thiel V, Johnston SL, Akdis CA, Sokolowska M. Radzikowska U, et al. Among authors: kebadze t. Nat Commun. 2023 Apr 22;14(1):2329. doi: 10.1038/s41467-023-37470-4. Nat Commun. 2023. PMID: 37087523 Free PMC article.
Acute exacerbations of chronic obstructive pulmonary disease: identification of biologic clusters and their biomarkers.
Bafadhel M, McKenna S, Terry S, Mistry V, Reid C, Haldar P, McCormick M, Haldar K, Kebadze T, Duvoix A, Lindblad K, Patel H, Rugman P, Dodson P, Jenkins M, Saunders M, Newbold P, Green RH, Venge P, Lomas DA, Barer MR, Johnston SL, Pavord ID, Brightling CE. Bafadhel M, et al. Among authors: kebadze t. Am J Respir Crit Care Med. 2011 Sep 15;184(6):662-71. doi: 10.1164/rccm.201104-0597OC. Am J Respir Crit Care Med. 2011. PMID: 21680942
Role of deficient type III interferon-lambda production in asthma exacerbations.
Contoli M, Message SD, Laza-Stanca V, Edwards MR, Wark PA, Bartlett NW, Kebadze T, Mallia P, Stanciu LA, Parker HL, Slater L, Lewis-Antes A, Kon OM, Holgate ST, Davies DE, Kotenko SV, Papi A, Johnston SL. Contoli M, et al. Among authors: kebadze t. Nat Med. 2006 Sep;12(9):1023-6. doi: 10.1038/nm1462. Epub 2006 Aug 13. Nat Med. 2006. PMID: 16906156
Rhinovirus-induced lower respiratory illness is increased in asthma and related to virus load and Th1/2 cytokine and IL-10 production.
Message SD, Laza-Stanca V, Mallia P, Parker HL, Zhu J, Kebadze T, Contoli M, Sanderson G, Kon OM, Papi A, Jeffery PK, Stanciu LA, Johnston SL. Message SD, et al. Among authors: kebadze t. Proc Natl Acad Sci U S A. 2008 Sep 9;105(36):13562-7. doi: 10.1073/pnas.0804181105. Epub 2008 Sep 3. Proc Natl Acad Sci U S A. 2008. PMID: 18768794 Free PMC article.
Defining critical roles for NF-κB p65 and type I interferon in innate immunity to rhinovirus.
Bartlett NW, Slater L, Glanville N, Haas JJ, Caramori G, Casolari P, Clarke DL, Message SD, Aniscenko J, Kebadze T, Zhu J, Mallia P, Mizgerd JP, Belvisi M, Papi A, Kotenko SV, Johnston SL, Edwards MR. Bartlett NW, et al. Among authors: kebadze t. EMBO Mol Med. 2012 Dec;4(12):1244-60. doi: 10.1002/emmm.201201650. Epub 2012 Nov 14. EMBO Mol Med. 2012. PMID: 23165884 Free PMC article.
Loss of regulatory capacity in Treg cells following rhinovirus infection.
Jansen K, Wirz OF, van de Veen W, Tan G, Mirer D, Sokolowska M, Satitsuksanoa P, Message SD, Kebadze T, Glanville N, Mallia P, Skiepko R, Eljaszewicz A, Moniuszko M, Cardoso C, Gern JE, Papadopoulos NG, Akdis CA, Johnston SL, Nadeau KC, Akdis M. Jansen K, et al. Among authors: kebadze t. J Allergy Clin Immunol. 2021 Oct;148(4):1016-1029.e16. doi: 10.1016/j.jaci.2021.05.045. Epub 2021 Jun 18. J Allergy Clin Immunol. 2021. PMID: 34153372
Experimental rhinovirus infection induces an antiviral response in circulating B cells which is dysregulated in patients with asthma.
Wirz OF, Jansen K, Satitsuksanoa P, van de Veen W, Tan G, Sokolowska M, Mirer D, Stanić B, Message SD, Kebadze T, Glanville N, Mallia P, Gern JE, Papadopoulos N, Akdis CA, Johnston SL, Nadeau K, Akdis M. Wirz OF, et al. Among authors: kebadze t. Allergy. 2022 Jan;77(1):130-142. doi: 10.1111/all.14985. Epub 2021 Jul 16. Allergy. 2022. PMID: 34169553 Free PMC article.
T regulatory cells from atopic asthmatic individuals show a Th2-like phenotype.
Jansen K, Satitsuksanoa P, Wirz OF, Schneider SR, van de Veen W, Tan G, Sokolowska M, Message SD, Kebadze T, Glanville N, Mallia P, Akdis CA, Moniuszko M, Johnston SL, Nadeau K, Akdis M. Jansen K, et al. Among authors: kebadze t. Allergy. 2022 Apr;77(4):1320-1324. doi: 10.1111/all.15193. Epub 2021 Dec 11. Allergy. 2022. PMID: 34862792 No abstract available.
Airway-delivered short-chain fatty acid acetate boosts antiviral immunity during rhinovirus infection.
Antunes KH, Singanayagam A, Williams L, Faiez TS, Farias A, Jackson MM, Faizi FK, Aniscenko J, Kebadze T, Chander Veerati P, Wood L, Bartlett NW, Duarte de Souza AP, Johnston SL. Antunes KH, et al. Among authors: kebadze t. J Allergy Clin Immunol. 2023 Feb;151(2):447-457.e5. doi: 10.1016/j.jaci.2022.09.026. Epub 2022 Oct 7. J Allergy Clin Immunol. 2023. PMID: 36216081 Free article.
46 results