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ONC201 in Combination with Paxalisib for the Treatment of H3K27-Altered Diffuse Midline Glioma.
Cancer Res. 2023 May 17:OF1-OF17. doi: 10.1158/0008-5472.CAN-23-0186. Online ahead of print.
Cancer Res. 2023.
PMID: 37195023
ONC201 in combination with paxalisib for the treatment of H3K27-altered diffuse midline glioma.
Jackson ER, Duchatel RJ, Staudt DE, Persson ML, Mannan A, Yadavilli S, Parackal S, Game S, Chong WC, Jayasekara WSN, Le Grand M, Kearney PS, Douglas AM, Findlay IJ, Germon ZP, McEwen HP, Beitaki TS, Patabendige A, Skerrett-Byrne DA, Nixon B, Smith ND, Day B, Manoharan N, Nagabushan S, Hansford JR, Govender D, McCowage GB, Firestein R, Howlett M, Endersby R, Gottardo NG, Alvaro F, Waszak SM, Larsen MR, Colino-Sanguino Y, Valdés-Mora F, Rakotomalala A, Meignan S, Pasquier E, Andre N, Hulleman E, Eisenstat DD, Vitanza NA, Nazarian J, Koschmann C, Mueller S, Cain JE, Dun MD.
Jackson ER, et al. Among authors: kearney ps.
Cancer Res. 2023 May 5;83(14):2421-37. doi: 10.1158/0008-5472.CAN-23-0186. Online ahead of print.
Cancer Res. 2023.
PMID: 37145169
Free PMC article.
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PI3K/mTOR is a therapeutically targetable genetic dependency in diffuse intrinsic pontine glioma.
Duchatel RJ, Jackson ER, Parackal SG, Kiltschewskij D, Findlay IJ, Mannan A, Staudt DE, Thomas BC, Germon ZP, Laternser S, Kearney PS, Jamaluddin MFB, Douglas AM, Beitaki T, McEwen HP, Persson ML, Hocke EA, Jain V, Aksu M, Manning EE, Murray HC, Verrills NM, Sun CX, Daniel P, Vilain RE, Skerrett-Byrne DA, Nixon B, Hua S, de Bock CE, Colino-Sanguino Y, Valdes-Mora F, Tsoli M, Ziegler DS, Cairns MJ, Raabe EH, Vitanza NA, Hulleman E, Phoenix TN, Koschmann C, Alvaro F, Dayas CV, Tinkle CL, Wheeler H, Whittle JR, Eisenstat DD, Firestein R, Mueller S, Valvi S, Hansford JR, Ashley DM, Gregory SG, Kilburn LB, Nazarian J, Cain JE, Dun MD.
Duchatel RJ, et al. Among authors: kearney ps.
J Clin Invest. 2024 Feb 6;134(6):e170329. doi: 10.1172/JCI170329.
J Clin Invest. 2024.
PMID: 38319732
Free PMC article.
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Holding on to Junk Bonds: Intron Retention in Cancer and Therapy.
Monteuuis G, Schmitz U, Petrova V, Kearney PS, Rasko JEJ.
Monteuuis G, et al. Among authors: kearney ps.
Cancer Res. 2021 Feb 15;81(4):779-789. doi: 10.1158/0008-5472.CAN-20-1943. Epub 2020 Oct 12.
Cancer Res. 2021.
PMID: 33046441
Review.
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Correction to: Phospho-heavy-labeled-spiketide FAIMS stepped-CV DDA (pHASED) provides real-time phosphoproteomics data to aid in cancer drug selection.
Staudt DE, Murray HC, Skerrett-Byrne DA, Smith ND, Jamaluddin MFB, Kahl RGS, Duchatel RJ, Germon ZP, McLachlan T, Jackson ER, Findlay IJ, Kearney PS, Mannan A, McEwen HP, Douglas AM, Nixon B, Verrills NM, Dun MD.
Staudt DE, et al. Among authors: kearney ps.
Clin Proteomics. 2023 Apr 8;20(1):16. doi: 10.1186/s12014-023-09406-z.
Clin Proteomics. 2023.
PMID: 37031204
Free PMC article.
No abstract available.
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Phospho-heavy-labeled-spiketide FAIMS stepped-CV DDA (pHASED) provides real-time phosphoproteomics data to aid in cancer drug selection.
Staudt DE, Murray HC, Skerrett-Byrne DA, Smith ND, Jamaluddin MFB, Kahl RGS, Duchatel RJ, Germon ZP, McLachlan T, Jackson ER, Findlay IJ, Kearney PS, Mannan A, McEwen HP, Douglas AM, Nixon B, Verrills NM, Dun MD.
Staudt DE, et al. Among authors: kearney ps.
Clin Proteomics. 2022 Dec 19;19(1):48. doi: 10.1186/s12014-022-09385-7.
Clin Proteomics. 2022.
PMID: 36536316
Free PMC article.
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Preclinical and clinical evaluation of German-sourced ONC201 for the treatment of H3K27M-mutant diffuse intrinsic pontine glioma.
Duchatel RJ, Mannan A, Woldu AS, Hawtrey T, Hindley PA, Douglas AM, Jackson ER, Findlay IJ, Germon ZP, Staudt D, Kearney PS, Smith ND, Hindley KE, Cain JE, André N, La Madrid AM, Nixon B, De Iuliis GN, Nazarian J, Irish K, Alvaro F, Eisenstat DD, Beck A, Vitanza NA, Mueller S, Morris JC, Dun MD.
Duchatel RJ, et al. Among authors: kearney ps.
Neurooncol Adv. 2021 Nov 19;3(1):vdab169. doi: 10.1093/noajnl/vdab169. eCollection 2021 Jan-Dec.
Neurooncol Adv. 2021.
PMID: 34988452
Free PMC article.
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