Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

75 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Characterization of Pharmacokinetics, Biotransformation and Elimination of Pomotrelvir Orally Administered in Healthy Male Adults Using Two [14C]-Labeled Microtracers with Separate Labeling Positions.
Yang Z, Wong SL, Cha D, Wilfret D, Turnquist D, Plummer A, van Ingen E, Kearney BP. Yang Z, et al. Among authors: kearney bp. Drug Metab Dispos. 2023 Dec;51(12):1607-1614. doi: 10.1124/dmd.123.001439. Epub 2023 Sep 8. Drug Metab Dispos. 2023. PMID: 37684056
A comprehensive evaluation in clinic and physiologically-based pharmacokinetic modeling and simulation to confirm lack of cytochrome P450-mediated drug-drug interaction potential for pomotrelvir.
Yang Z, Rioux N, Vincent L, Jones HM, Cha D, Plummer A, Wilfret D, Kearney BP. Yang Z, et al. Among authors: kearney bp. CPT Pharmacometrics Syst Pharmacol. 2023 Oct;12(10):1553-1564. doi: 10.1002/psp4.13034. Epub 2023 Aug 30. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 37614073 Free PMC article.
Exposure-response relationships for the efficacy and safety of filgotinib and its metabolite GS-829845 in subjects with rheumatoid arthritis based on phase 2 and phase 3 studies.
Meng A, Anderson K, Nelson C, Ni L, Chuang SM, Bellanti F, Chang P, Comisar C, Kearney BP, Bartok B, Mathias A. Meng A, et al. Among authors: kearney bp. Br J Clin Pharmacol. 2022 Jul;88(7):3211-3221. doi: 10.1111/bcp.15239. Epub 2022 Feb 14. Br J Clin Pharmacol. 2022. PMID: 35072287 Free PMC article. Clinical Trial.
Organic Anion Transporting Polypeptide Inhibition Dramatically Increases Plasma Exposure but not Pharmacodynamic Effect nor Inferred Hepatic Intracellular Exposure of Firsocostat.
Kirby BJ, Lutz JD, Yue MS, Garrison KL, Qin AR, Ampaw L, Beysen C, Myers RP, Kearney BP, Mathias A. Kirby BJ, et al. Among authors: kearney bp. Clin Pharmacol Ther. 2021 May;109(5):1334-1341. doi: 10.1002/cpt.2105. Epub 2020 Nov 25. Clin Pharmacol Ther. 2021. PMID: 33141923 Clinical Trial.
An LC-MS/MS method for determination of tenofovir (TFV) in human plasma following tenofovir alafenamide (TAF) administration: Development, validation, cross-validation, and use of formic acid as plasma TFV stabilizer.
Xiao D, Ling KHJ, Tarnowski T, Majeed SR, German P, Kearney BP, Zhao Y, Chen YS, Ma L, Zhang T. Xiao D, et al. Among authors: kearney bp. Anal Biochem. 2020 Mar 15;593:113611. doi: 10.1016/j.ab.2020.113611. Epub 2020 Feb 5. Anal Biochem. 2020. PMID: 32035040
75 results