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Function-oriented development of CXCR4 antagonists as selective human immunodeficiency virus (HIV)-1 entry inhibitors.
Wu CH, Wang CJ, Chang CP, Cheng YC, Song JS, Jan JJ, Chou MC, Ke YY, Ma J, Wong YC, Hsieh TC, Tien YC, Gullen EA, Lo CF, Cheng CY, Liu YW, Sadani AA, Tsai CH, Hsieh HP, Tsou LK, Shia KS. Wu CH, et al. Among authors: ke yy. J Med Chem. 2015 Feb 12;58(3):1452-65. doi: 10.1021/jm501772w. Epub 2015 Jan 28. J Med Chem. 2015. PMID: 25584630 Free PMC article.
Discovery, structure-activity relationship studies, and anti-nociceptive effects of N-(1,2,3,4-tetrahydro-1-isoquinolinylmethyl)benzamides as novel opioid receptor agonists.
Chen SR, Ke YY, Yeh TK, Lin SY, Ou LC, Chen SC, Chang WT, Chang HF, Wu ZH, Hsieh CC, Law PY, Loh HH, Shih C, Lai YK, Yeh SH, Ueng SH. Chen SR, et al. Among authors: ke yy. Eur J Med Chem. 2017 Jan 27;126:202-217. doi: 10.1016/j.ejmech.2016.09.003. Epub 2016 Sep 20. Eur J Med Chem. 2017. PMID: 27776274
Discovery of BPR1K871, a quinazoline based, multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation.
Hsu YC, Coumar MS, Wang WC, Shiao HY, Ke YY, Lin WH, Kuo CC, Chang CW, Kuo FM, Chen PY, Wang SY, Li AS, Chen CH, Kuo PC, Chen CP, Wu MH, Huang CL, Yen KJ, Chang YI, Hsu JT, Chen CT, Yeh TK, Song JS, Shih C, Hsieh HP. Hsu YC, et al. Among authors: ke yy. Oncotarget. 2016 Dec 27;7(52):86239-86256. doi: 10.18632/oncotarget.13369. Oncotarget. 2016. PMID: 27863392 Free PMC article.
Bromomethylthioindole Inspired Carbazole Hybrids as Promising Class of Anti-MRSA Agents.
Cheng CY, Chang CP, Lauderdale TY, Yu GY, Lee JC, Jhang YW, Wu CH, Ke YY, Sadani AA, Yeh CF, Huang IW, Kuo YP, Tsai DJ, Yeh TK, Tseng CT, Song JS, Liu YW, Tsou LK, Shia KS. Cheng CY, et al. Among authors: ke yy. ACS Med Chem Lett. 2016 Oct 21;7(12):1191-1196. doi: 10.1021/acsmedchemlett.6b00289. eCollection 2016 Dec 8. ACS Med Chem Lett. 2016. PMID: 27994762 Free PMC article.
89 results