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Quaking promotes monocyte differentiation into pro-atherogenic macrophages by controlling pre-mRNA splicing and gene expression.
de Bruin RG, Shiue L, Prins J, de Boer HC, Singh A, Fagg WS, van Gils JM, Duijs JM, Katzman S, Kraaijeveld AO, Böhringer S, Leung WY, Kielbasa SM, Donahue JP, van der Zande PH, Sijbom R, van Alem CM, Bot I, van Kooten C, Jukema JW, Van Esch H, Rabelink TJ, Kazan H, Biessen EA, Ares M Jr, van Zonneveld AJ, van der Veer EP. de Bruin RG, et al. Among authors: kazan h. Nat Commun. 2016 Mar 31;7:10846. doi: 10.1038/ncomms10846. Nat Commun. 2016. PMID: 27029405 Free PMC article.
LIN28 binds messenger RNAs at GGAGA motifs and regulates splicing factor abundance.
Wilbert ML, Huelga SC, Kapeli K, Stark TJ, Liang TY, Chen SX, Yan BY, Nathanson JL, Hutt KR, Lovci MT, Kazan H, Vu AQ, Massirer KB, Morris Q, Hoon S, Yeo GW. Wilbert ML, et al. Among authors: kazan h. Mol Cell. 2012 Oct 26;48(2):195-206. doi: 10.1016/j.molcel.2012.08.004. Epub 2012 Sep 6. Mol Cell. 2012. PMID: 22959275 Free PMC article.
A compendium of RNA-binding motifs for decoding gene regulation.
Ray D, Kazan H, Cook KB, Weirauch MT, Najafabadi HS, Li X, Gueroussov S, Albu M, Zheng H, Yang A, Na H, Irimia M, Matzat LH, Dale RK, Smith SA, Yarosh CA, Kelly SM, Nabet B, Mecenas D, Li W, Laishram RS, Qiao M, Lipshitz HD, Piano F, Corbett AH, Carstens RP, Frey BJ, Anderson RA, Lynch KW, Penalva LO, Lei EP, Fraser AG, Blencowe BJ, Morris QD, Hughes TR. Ray D, et al. Among authors: kazan h. Nature. 2013 Jul 11;499(7457):172-7. doi: 10.1038/nature12311. Nature. 2013. PMID: 23846655 Free PMC article.
Finding the target sites of RNA-binding proteins.
Li X, Kazan H, Lipshitz HD, Morris QD. Li X, et al. Among authors: kazan h. Wiley Interdiscip Rev RNA. 2014 Jan-Feb;5(1):111-30. doi: 10.1002/wrna.1201. Epub 2013 Nov 11. Wiley Interdiscip Rev RNA. 2014. PMID: 24217996 Free PMC article. Review.
miR-223 Exerts Translational Control of Proatherogenic Genes in Macrophages.
Nguyen MA, Hoang HD, Rasheed A, Duchez AC, Wyatt H, Cottee ML, Graber TE, Susser L, Robichaud S, Berber İ, Geoffrion M, Ouimet M, Kazan H, Maegdefessel L, Mulvihill EE, Alain T, Rayner KJ. Nguyen MA, et al. Among authors: kazan h. Circ Res. 2022 Jun 24;131(1):42-58. doi: 10.1161/CIRCRESAHA.121.319120. Epub 2022 May 25. Circ Res. 2022. PMID: 35611698 Free PMC article.
62 results