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Page 1
Neutrophil oxidative stress mediates obesity-associated vascular dysfunction and metastatic transmigration.
McDowell SAC, Luo RBE, Arabzadeh A, Doré S, Bennett NC, Breton V, Karimi E, Rezanejad M, Yang RR, Lach KD, Issac MSM, Samborska B, Perus LJM, Moldoveanu D, Wei Y, Fiset B, Rayes RF, Watson IR, Kazak L, Guiot MC, Fiset PO, Spicer JD, Dannenberg AJ, Walsh LA, Quail DF. McDowell SAC, et al. Among authors: kazak l. Nat Cancer. 2021 May;2(5):545-562. doi: 10.1038/s43018-021-00194-9. Epub 2021 May 3. Nat Cancer. 2021. PMID: 35122017
Accumulation of succinate controls activation of adipose tissue thermogenesis.
Mills EL, Pierce KA, Jedrychowski MP, Garrity R, Winther S, Vidoni S, Yoneshiro T, Spinelli JB, Lu GZ, Kazak L, Banks AS, Haigis MC, Kajimura S, Murphy MP, Gygi SP, Clish CB, Chouchani ET. Mills EL, et al. Among authors: kazak l. Nature. 2018 Aug;560(7716):102-106. doi: 10.1038/s41586-018-0353-2. Epub 2018 Jul 18. Nature. 2018. PMID: 30022159 Free PMC article.
Creatine-mediated crosstalk between adipocytes and cancer cells regulates obesity-driven breast cancer.
Maguire OA, Ackerman SE, Szwed SK, Maganti AV, Marchildon F, Huang X, Kramer DJ, Rosas-Villegas A, Gelfer RG, Turner LE, Ceballos V, Hejazi A, Samborska B, Rahbani JF, Dykstra CB, Annis MG, Luo JD, Carroll TS, Jiang CS, Dannenberg AJ, Siegel PM, Tersey SA, Mirmira RG, Kazak L, Cohen P. Maguire OA, et al. Among authors: kazak l. Cell Metab. 2021 Mar 2;33(3):499-512.e6. doi: 10.1016/j.cmet.2021.01.018. Epub 2021 Feb 16. Cell Metab. 2021. PMID: 33596409 Free PMC article.
Creatine kinase B controls futile creatine cycling in thermogenic fat.
Rahbani JF, Roesler A, Hussain MF, Samborska B, Dykstra CB, Tsai L, Jedrychowski MP, Vergnes L, Reue K, Spiegelman BM, Kazak L. Rahbani JF, et al. Among authors: kazak l. Nature. 2021 Feb;590(7846):480-485. doi: 10.1038/s41586-021-03221-y. Epub 2021 Feb 17. Nature. 2021. PMID: 33597756 Free PMC article.
Mitochondrial TNAP controls thermogenesis by hydrolysis of phosphocreatine.
Sun Y, Rahbani JF, Jedrychowski MP, Riley CL, Vidoni S, Bogoslavski D, Hu B, Dumesic PA, Zeng X, Wang AB, Knudsen NH, Kim CR, Marasciullo A, Millán JL, Chouchani ET, Kazak L, Spiegelman BM. Sun Y, et al. Among authors: kazak l. Nature. 2021 May;593(7860):580-585. doi: 10.1038/s41586-021-03533-z. Epub 2021 May 12. Nature. 2021. PMID: 33981039 Free PMC article.
ADRA1A-Gαq signalling potentiates adipocyte thermogenesis through CKB and TNAP.
Rahbani JF, Scholtes C, Lagarde DM, Hussain MF, Roesler A, Dykstra CB, Bunk J, Samborska B, O'Brien SL, Tripp E, Pacis A, Angueira AR, Johansen OS, Cinkornpumin J, Hossain I, Lynes MD, Zhang Y, White AP, Pastor WA, Chondronikola M, Sidossis L, Klein S, Kralli A, Cypess AM, Pedersen SB, Jessen N, Tseng YH, Gerhart-Hines Z, Seale P, Calebiro D, Giguère V, Kazak L. Rahbani JF, et al. Among authors: kazak l. Nat Metab. 2022 Nov;4(11):1459-1473. doi: 10.1038/s42255-022-00667-w. Epub 2022 Nov 7. Nat Metab. 2022. PMID: 36344764 Free PMC article.
Parallel control of cold-triggered adipocyte thermogenesis by UCP1 and CKB.
Rahbani JF, Bunk J, Lagarde D, Samborska B, Roesler A, Xiao H, Shaw A, Kaiser Z, Braun JL, Geromella MS, Fajardo VA, Koza RA, Kazak L. Rahbani JF, et al. Among authors: kazak l. Cell Metab. 2024 Mar 5;36(3):526-540.e7. doi: 10.1016/j.cmet.2024.01.001. Epub 2024 Jan 24. Cell Metab. 2024. PMID: 38272036
101 results