Kayed R - Search Results

1

Amyloid Oligomers: A Joint Experimental/Computational Perspective on Alzheimer's Disease, Parkinson's Disease, Type II Diabetes, and Amyotrophic Lateral Sclerosis.

Nguyen PH, Ramamoorthy A, Sahoo BR, Zheng J, Faller P, Straub JE, Dominguez L, Shea JE, Dokholyan NV, De Simone A, Ma B, Nussinov R, Najafi S, Ngo ST, Loquet A, Chiricotto M, Ganguly P, McCarty J, Li MS, Hall C, Wang Y, Miller Y, Melchionna S, Habenstein B, Timr S, Chen J, Hnath B, Strodel B, Kayed R, Lesné S, Wei G, Sterpone F, Doig AJ, Derreumaux P. Nguyen PH, et al. Among authors: kayed r. Chem Rev. 2021 Feb 24;121(4):2545-2647. doi: 10.1021/acs.chemrev.0c01122. Epub 2021 Feb 5. Chem Rev. 2021. PMID: 33543942 Free PMC article. Review.

2

A specific amyloid-beta protein assembly in the brain impairs memory.

Lesné S, Koh MT, Kotilinek L, Kayed R, Glabe CG, Yang A, Gallagher M, Ashe KH. Lesné S, et al. Among authors: kayed r. Nature. 2006 Mar 16;440(7082):352-7. doi: 10.1038/nature04533. Nature. 2006. PMID: 16541076

3

Anti-tau oligomers passive vaccination for the treatment of Alzheimer disease.

Kayed R. Kayed R. Hum Vaccin. 2010 Nov;6(11):931-5. doi: 10.4161/hv.6.11.12689. Epub 2010 Nov 1. Hum Vaccin. 2010. PMID: 20980799 Review.

4

Preparation and characterization of neurotoxic tau oligomers.

Lasagna-Reeves CA, Castillo-Carranza DL, Guerrero-Muoz MJ, Jackson GR, Kayed R. Lasagna-Reeves CA, et al. Among authors: kayed r. Biochemistry. 2010 Nov 30;49(47):10039-41. doi: 10.1021/bi1016233. Epub 2010 Nov 8. Biochemistry. 2010. PMID: 21047142

5

Amyloid-β annular protofibrils evade fibrillar fate in Alzheimer disease brain.

Lasagna-Reeves CA, Glabe CG, Kayed R. Lasagna-Reeves CA, et al. Among authors: kayed r. J Biol Chem. 2011 Jun 24;286(25):22122-30. doi: 10.1074/jbc.M111.236257. Epub 2011 Apr 20. J Biol Chem. 2011. PMID: 21507938 Free PMC article.

6

Astrocytes contain amyloid-β annular protofibrils in Alzheimer's disease brains.

Lasagna-Reeves CA, Kayed R. Lasagna-Reeves CA, et al. Among authors: kayed r. FEBS Lett. 2011 Oct 3;585(19):3052-7. doi: 10.1016/j.febslet.2011.08.027. Epub 2011 Aug 24. FEBS Lett. 2011. PMID: 21872592 Free article.

7

Molecular mechanisms of amyloid oligomers toxicity.

Kayed R, Lasagna-Reeves CA. Kayed R, et al. J Alzheimers Dis. 2013;33 Suppl 1:S67-78. doi: 10.3233/JAD-2012-129001. J Alzheimers Dis. 2013. PMID: 22531422 Review.

8

Design of metastable β-sheet oligomers from natively unstructured peptide.

Guerrero-Muñoz MJ, Castillo-Carranza DL, Sengupta U, White MA, Kayed R. Guerrero-Muñoz MJ, et al. Among authors: kayed r. ACS Chem Neurosci. 2013 Dec 18;4(12):1520-3. doi: 10.1021/cn4001395. Epub 2013 Oct 14. ACS Chem Neurosci. 2013. PMID: 24106878 Free PMC article.

9

Advances in therapeutics for neurodegenerative tauopathies: moving toward the specific targeting of the most toxic tau species.

Gerson JE, Castillo-Carranza DL, Kayed R. Gerson JE, et al. Among authors: kayed r. ACS Chem Neurosci. 2014 Sep 17;5(9):752-69. doi: 10.1021/cn500143n. Epub 2014 Aug 8. ACS Chem Neurosci. 2014. PMID: 25075869 Review.

10

Amyloid-β oligomers as a template for secondary amyloidosis in Alzheimer's disease.

Guerrero-Muñoz MJ, Castillo-Carranza DL, Krishnamurthy S, Paulucci-Holthauzen AA, Sengupta U, Lasagna-Reeves CA, Ahmad Y, Jackson GR, Kayed R. Guerrero-Muñoz MJ, et al. Among authors: kayed r. Neurobiol Dis. 2014 Nov;71:14-23. doi: 10.1016/j.nbd.2014.08.008. Epub 2014 Aug 15. Neurobiol Dis. 2014. PMID: 25134727

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