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Desmoglein-2 is important for islet function and β-cell survival.
Myo Min KK, Rojas-Canales D, Penko D, DeNichilo M, Cockshell MP, Ffrench CB, Thompson EJ, Asplund O, Drogemuller CJ, Prasad RB, Groop L, Grey ST, Thomas HE, Loudovaris T, Kay TW, Mahoney MG, Jessup CF, Coates PT, Bonder CS. Myo Min KK, et al. Among authors: kay tw. Cell Death Dis. 2022 Oct 29;13(10):911. doi: 10.1038/s41419-022-05326-2. Cell Death Dis. 2022. PMID: 36309486 Free PMC article.
Diabetes induced by checkpoint inhibition in nonobese diabetic mice can be prevented or reversed by a JAK1/JAK2 inhibitor.
Ge T, Phung AL, Jhala G, Trivedi P, Principe N, De George DJ, Pappas EG, Litwak S, Sanz-Villanueva L, Catterall T, Fynch S, Boon L, Kay TW, Chee J, Krishnamurthy B, Thomas HE. Ge T, et al. Among authors: kay tw. Clin Transl Immunology. 2022 Oct 30;11(11):e1425. doi: 10.1002/cti2.1425. eCollection 2022. Clin Transl Immunology. 2022. PMID: 36325490 Free PMC article.
Longitudinal Assessment of Pancreas Volume by MRI Predicts Progression to Stage 3 Type 1 Diabetes.
Virostko J, Wright JJ, Williams JM, Hilmes MA, Triolo TM, Broncucia H, Du L, Kang H, Nallaparaju S, Valencia LG, Reyes D, Hammel B, Russell WE, Philipson LH, Waibel M, Kay TWH, Thomas HE, Greeley SAW, Steck AK, Powers AC, Moore DJ. Virostko J, et al. Among authors: kay twh. Diabetes Care. 2024 Mar 1;47(3):393-400. doi: 10.2337/dc23-1681. Diabetes Care. 2024. PMID: 38151474 Free PMC article.
Imaging for assessment of cancer treatment response to immune checkpoint inhibitors can be complementary in identifying hypophysitis.
Galligan A, Iravani A, Lasocki A, Wallace R, Weppler AM, Sachithanandan N, Chiang C, Colman PG, Wentworth J, Spain L, Au-Yeung G, Lee B, Kay TWH, Hicks RJ, Sandhu S, Krishnamurthy B. Galligan A, et al. Among authors: kay twh. Front Endocrinol (Lausanne). 2023 Nov 29;14:1295865. doi: 10.3389/fendo.2023.1295865. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 38093958 Free PMC article.
Baricitinib and β-Cell Function in Patients with New-Onset Type 1 Diabetes.
Waibel M, Wentworth JM, So M, Couper JJ, Cameron FJ, MacIsaac RJ, Atlas G, Gorelik A, Litwak S, Sanz-Villanueva L, Trivedi P, Ahmed S, Martin FJ, Doyle ME, Harbison JE, Hall C, Krishnamurthy B, Colman PG, Harrison LC, Thomas HE, Kay TWH; BANDIT Study Group. Waibel M, et al. Among authors: kay twh. N Engl J Med. 2023 Dec 7;389(23):2140-2150. doi: 10.1056/NEJMoa2306691. N Engl J Med. 2023. PMID: 38055252 Clinical Trial.
211 results