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Oral immunization with a Lactobacillus casei vaccine expressing human papillomavirus (HPV) type 16 E7 is an effective strategy to induce mucosal cytotoxic lymphocytes against HPV16 E7.
Adachi K, Kawana K, Yokoyama T, Fujii T, Tomio A, Miura S, Tomio K, Kojima S, Oda K, Sewaki T, Yasugi T, Kozuma S, Taketani Y. Adachi K, et al. Among authors: kawana k. Vaccine. 2010 Apr 1;28(16):2810-7. doi: 10.1016/j.vaccine.2010.02.005. Epub 2010 Feb 17. Vaccine. 2010. PMID: 20170766
Adjuvant effect of Japanese herbal medicines on the mucosal type 1 immune responses to human papillomavirus (HPV) E7 in mice immunized orally with Lactobacillus-based therapeutic HPV vaccine in a synergistic manner.
Taguchi A, Kawana K, Yokoyama T, Adachi K, Yamashita A, Tomio K, Kojima S, Oda K, Fujii T, Kozuma S. Taguchi A, et al. Among authors: kawana k. Vaccine. 2012 Aug 3;30(36):5368-72. doi: 10.1016/j.vaccine.2012.06.027. Epub 2012 Jun 21. Vaccine. 2012. PMID: 22727726
Oral vaccination against HPV E7 for treatment of cervical intraepithelial neoplasia grade 3 (CIN3) elicits E7-specific mucosal immunity in the cervix of CIN3 patients.
Kawana K, Adachi K, Kojima S, Taguchi A, Tomio K, Yamashita A, Nishida H, Nagasaka K, Arimoto T, Yokoyama T, Wada-Hiraike O, Oda K, Sewaki T, Osuga Y, Fujii T. Kawana K, et al. Vaccine. 2014 Oct 29;32(47):6233-9. doi: 10.1016/j.vaccine.2014.09.020. Epub 2014 Sep 22. Vaccine. 2014. PMID: 25258102 Clinical Trial.
319 results