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Inhibition of stearoyl-CoA desaturase 1 (SCD1) enhances the antitumor T cell response through regulating β-catenin signaling in cancer cells and ER stress in T cells and synergizes with anti-PD-1 antibody.
Katoh Y, Yaguchi T, Kubo A, Iwata T, Morii K, Kato D, Ohta S, Satomi R, Yamamoto Y, Oyamada Y, Ouchi K, Takahashi S, Ishioka C, Matoba R, Suematsu M, Kawakami Y. Katoh Y, et al. Among authors: kawakami y. J Immunother Cancer. 2022 Jul;10(7):e004616. doi: 10.1136/jitc-2022-004616. J Immunother Cancer. 2022. PMID: 35793868 Free PMC article.
Adoptive cell therapy using tumor-infiltrating lymphocytes for melanoma refractory to immune-checkpoint inhibitors.
Hirai I, Funakoshi T, Kamijuku H, Fukuda K, Mori M, Sakurai M, Koda Y, Kato J, Mori T, Watanabe N, Noji S, Yaguchi T, Iwata T, Ohta S, Fujita T, Tanosaki R, Handa M, Okamoto S, Amagai M, Kawakami Y. Hirai I, et al. Among authors: kawakami y. Cancer Sci. 2021 Aug;112(8):3163-3172. doi: 10.1111/cas.15009. Epub 2021 Jun 30. Cancer Sci. 2021. PMID: 34101300 Free PMC article. Clinical Trial.
2,797 results