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Soluble Sema4D cleaved from osteoclast precursors by TACE suppresses osteoblastogenesis.
Ishii T, Ruiz-Torruella M, Kim JY, Kanzaki H, Albassam A, Wisitrasameewong W, Shindo S, Pierrelus R, Heidari A, Kandalam U, Nakamura S, Movila A, Minond D, Kawai T. Ishii T, et al. Among authors: kawai t. J Cell Mol Med. 2023 Jun;27(12):1750-1756. doi: 10.1111/jcmm.17416. Epub 2023 May 11. J Cell Mol Med. 2023. PMID: 37170687 Free PMC article.
OC-STAMP promotes osteoclast fusion for pathogenic bone resorption in periodontitis via up-regulation of permissive fusogen CD9.
Ishii T, Ruiz-Torruella M, Ikeda A, Shindo S, Movila A, Mawardi H, Albassam A, Kayal RA, Al-Dharrab AA, Egashira K, Wisitrasameewong W, Yamamoto K, Mira AI, Sueishi K, Han X, Taubman MA, Miyamoto T, Kawai T. Ishii T, et al. Among authors: kawai t. FASEB J. 2018 Jul;32(7):4016-4030. doi: 10.1096/fj.201701424R. Epub 2018 Mar 13. FASEB J. 2018. PMID: 29533736 Free PMC article.
The present study demonstrated that OC-STAMP partners CD9 to promote periodontal bone destruction by up-regulation of fusion during osteoclastogenesis, suggesting that anti-OC-STAMP-mAb may lead to the development of a novel therapeutic regimen for periodontitis.-Ishii, T. …
The present study demonstrated that OC-STAMP partners CD9 to promote periodontal bone destruction by up-regulation of fusion during osteocla …
Locally Secreted Semaphorin 4D Is Engaged in Both Pathogenic Bone Resorption and Retarded Bone Regeneration in a Ligature-Induced Mouse Model of Periodontitis.
Ishii T, Ruiz-Torruella M, Yamamoto K, Yamaguchi T, Heidari A, Pierrelus R, Leon E, Shindo S, Rawas-Qalaji M, Pastore MR, Ikeda A, Nakamura S, Mawardi H, Kandalam U, Hardigan P, Witek L, Coelho PG, Kawai T. Ishii T, et al. Among authors: kawai t. Int J Mol Sci. 2022 May 18;23(10):5630. doi: 10.3390/ijms23105630. Int J Mol Sci. 2022. PMID: 35628440 Free PMC article.
Extracellular Release of Citrullinated Vimentin Directly Acts on Osteoclasts to Promote Bone Resorption in a Mouse Model of Periodontitis.
Shindo S, Pierrelus R, Ikeda A, Nakamura S, Heidari A, Pastore MR, Leon E, Ruiz S, Chheda H, Khatiwala R, Kumagai T, Tolson G, Elderbashy I, Ouhara K, Han X, Hernandez M, Vardar-Sengul S, Shiba H, Kawai T. Shindo S, et al. Among authors: kawai t. Cells. 2023 Apr 8;12(8):1109. doi: 10.3390/cells12081109. Cells. 2023. PMID: 37190018 Free PMC article.
TRAP-positive osteoclast precursors mediate ROS/NO-dependent bactericidal activity via TLR4.
Nishimura K, Shindo S, Movila A, Kayal R, Abdullah A, Savitri IJ, Ikeda A, Yamaguchi T, Howait M, Al-Dharrab A, Mira A, Han X, Kawai T. Nishimura K, et al. Among authors: kawai t. Free Radic Biol Med. 2016 Aug;97:330-341. doi: 10.1016/j.freeradbiomed.2016.06.021. Epub 2016 Jun 22. Free Radic Biol Med. 2016. PMID: 27343691 Free PMC article.
Proinflammatory M1 Macrophages Inhibit RANKL-Induced Osteoclastogenesis.
Yamaguchi T, Movila A, Kataoka S, Wisitrasameewong W, Ruiz Torruella M, Murakoshi M, Murakami S, Kawai T. Yamaguchi T, et al. Among authors: kawai t. Infect Immun. 2016 Sep 19;84(10):2802-12. doi: 10.1128/IAI.00461-16. Print 2016 Oct. Infect Immun. 2016. PMID: 27456834 Free PMC article.
3,762 results