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Secondary prevention of stroke: Pleiotropic effects of optimal oral pharmacotherapy.
Kikuchi K, Kawahara KI, Miura N, Ito T, Morimoto Y, Tancharoen S, Takeshige N, Uchikado H, Sakamoto R, Miyagi N, Kikuchi C, Iida N, Shiomi N, Kuramoto T, Hirohata M, Maruyama I, Morioka M, Tanaka E. Kikuchi K, et al. Among authors: kawahara ki. Exp Ther Med. 2012 Jul;4(1):3-7. doi: 10.3892/etm.2012.560. Epub 2012 Apr 24. Exp Ther Med. 2012. PMID: 23060914 Free PMC article.
Edaravone, a Synthetic Free Radical Scavenger, Enhances Alteplase-Mediated Thrombolysis.
Kikuchi K, Setoyama K, Kawahara KI, Nagasato T, Terashi T, Ueda K, Nakanishi K, Otsuka S, Miura N, Sameshima H, Hosokawa K, Harada Y, Shrestha B, Yamamoto M, Morimoto-Yamashita Y, Kikuchi H, Kiyama R, Kamikokuryo C, Tancharoen S, Sakakima H, Morioka M, Tanaka E, Ito T, Maruyama I. Kikuchi K, et al. Among authors: kawahara ki. Oxid Med Cell Longev. 2017;2017:6873281. doi: 10.1155/2017/6873281. Epub 2017 Nov 10. Oxid Med Cell Longev. 2017. PMID: 29259732 Free PMC article.
Uric acid enhances alteplase-mediated thrombolysis as an antioxidant.
Kikuchi K, Setoyama K, Tanaka E, Otsuka S, Terashi T, Nakanishi K, Takada S, Sakakima H, Ampawong S, Kawahara KI, Nagasato T, Hosokawa K, Harada Y, Yamamoto M, Kamikokuryo C, Kiyama R, Morioka M, Ito T, Maruyama I, Tancharoen S. Kikuchi K, et al. Among authors: kawahara ki. Sci Rep. 2018 Oct 26;8(1):15844. doi: 10.1038/s41598-018-34220-1. Sci Rep. 2018. PMID: 30367108 Free PMC article.
TLR4/MD-2 is a receptor for extracellular nucleophosmin 1.
Nakatomi K, Ueno H, Ishikawa Y, Salim RC, Mori Y, Kanemoto I, Tancharoen S, Kikuchi K, Miura N, Omori T, Okuda-Ashitaka E, Matsumura K, Imaizumi H, Motomiya Y, Maruyama I, Kawahara KI. Nakatomi K, et al. Among authors: kawahara ki. Biomed Rep. 2021 Feb;14(2):21. doi: 10.3892/br.2020.1397. Epub 2020 Dec 2. Biomed Rep. 2021. PMID: 33335727 Free PMC article.
The free radical scavenger edaravone rescues rats from cerebral infarction by attenuating the release of high-mobility group box-1 in neuronal cells.
Kikuchi K, Kawahara K, Tancharoen S, Matsuda F, Morimoto Y, Ito T, Biswas KK, Takenouchi K, Miura N, Oyama Y, Nawa Y, Arimura N, Iwata M, Tajima Y, Kuramoto T, Nakayama K, Shigemori M, Yoshida Y, Hashiguchi T, Maruyama I. Kikuchi K, et al. J Pharmacol Exp Ther. 2009 Jun;329(3):865-74. doi: 10.1124/jpet.108.149484. Epub 2009 Mar 17. J Pharmacol Exp Ther. 2009. PMID: 19293391
Edaravone attenuates cerebral ischemic injury by suppressing aquaporin-4.
Kikuchi K, Tancharoen S, Matsuda F, Biswas KK, Ito T, Morimoto Y, Oyama Y, Takenouchi K, Miura N, Arimura N, Nawa Y, Meng X, Shrestha B, Arimura S, Iwata M, Mera K, Sameshima H, Ohno Y, Maenosono R, Tajima Y, Uchikado H, Kuramoto T, Nakayama K, Shigemori M, Yoshida Y, Hashiguchi T, Maruyama I, Kawahara K. Kikuchi K, et al. Biochem Biophys Res Commun. 2009 Dec 25;390(4):1121-5. doi: 10.1016/j.bbrc.2009.09.015. Epub 2009 Sep 6. Biochem Biophys Res Commun. 2009. PMID: 19737535
Edaravone: a new therapeutic approach for the treatment of acute stroke.
Kikuchi K, Kawahara K, Miyagi N, Uchikado H, Kuramoto T, Morimoto Y, Tancharoen S, Miura N, Takenouchi K, Oyama Y, Shrestha B, Matsuda F, Yoshida Y, Arimura S, Mera K, Tada K, Yoshinaga N, Maenosono R, Ohno Y, Hashiguchi T, Maruyama I, Shigemori M. Kikuchi K, et al. Med Hypotheses. 2010 Dec;75(6):583-5. doi: 10.1016/j.mehy.2010.07.038. Epub 2010 Aug 21. Med Hypotheses. 2010. PMID: 20728280
88 results